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Thiocarbamide

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Identification
Molecular formula
C6H10N4S
CAS number
62-56-6
IUPAC name
3-[1-(4-pyridyl)ethylideneamino]isothiourea
State
State

At room temperature, thiocarbamide is a solid. It is relatively stable, but it should be stored in a well-ventilated area away from strong oxidizing agents to maintain its integrity.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
76.13g/mol
Molar mass
76.1300g/mol
Density
1.3870g/cm3
Appearence

Thiocarbamide, also known as thiourea, typically appears as a white or off-white crystalline solid. The compound is often in the form of granules or powder, and its crystals can also be hexagonal in shape. It may have a faint odor similar to sulfur compounds.

Comment on solubility

Solubility of 3-[1-(4-pyridyl)ethylideneamino]isothiourea

The solubility of 3-[1-(4-pyridyl)ethylideneamino]isothiourea is an intriguing topic that reflects the compound's unique structural features. This compound, owing to its functional groups, exhibits distinct solubility properties in various solvents.

Factors Influencing Solubility:

  • Polarity: The presence of the pyridyl group and the amino moiety contributes to the overall polarity, allowing for interaction with polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in protic solvents like water.
  • Temperature: As with many compounds, solubility may increase with temperature, enabling better dissolution characteristics.

Generally, 3-[1-(4-pyridyl)ethylideneamino]isothiourea is expected to have reasonable solubility in polar organic solvents such as DMSO or ethanol, while its solubility in nonpolar solvents may be markedly lower.

In summary, the solubility of this compound can be described as:

  1. Good in polar solvents due to polarity and hydrogen bonding.
  2. Poor in nonpolar solvents.

Understanding these solubility characteristics is essential for applications involving this compound in various chemical contexts.

Interesting facts

Interesting Facts about 3-[1-(4-pyridyl)ethylideneamino]isothiourea

3-[1-(4-pyridyl)ethylideneamino]isothiourea is a fascinating compound that bridges organic chemistry and medicinal applications. Here are some intriguing aspects about this compound:

  • Structural Complexity: This compound features a unique isothiourea functional group, which has been noted for its diverse reactivity and versatility in organic synthesis.
  • Biological Significance: Isothioureas, like this compound, are often studied for their potential as inhibitors in biological processes, especially in the context of cancer research and enzyme inhibition.
  • Pyridyl Ring: The presence of a pyridyl ring enhances the compound's properties significantly, making it a prime candidate for further research in pharmacology due to its potential interactions with biological targets.
  • Research Applications: This compound can serve as a valuable building block for synthesizing new drugs or compounds with specific biological activities, thus playing a crucial role in the development of novel therapeutics.
  • Potential Antimicrobial Activity: Preliminary studies suggest that compounds with isothiourea functionality may exhibit antimicrobial properties, leading to their exploration in the development of new antibiotics.

In summary, 3-[1-(4-pyridyl)ethylideneamino]isothiourea encapsulates a blend of structural diversity and biological utility, making it a compound of interest both in academic research and pharmaceutical development. As stated by researchers, "the integration of heterocycles, like pyridine, into isothioureas opens new pathways in drug discovery." With ongoing studies, its full potential may soon be unveiled, showcasing the remarkable relationship between compound structure and function.