Interesting facts
Interesting Facts about 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one
The compound 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one is noteworthy in the field of medicinal chemistry due to its complex structure and potential applications. Here are some fascinating insights about this compound:
- Structure Complexity: The distinctive arrangement of atoms in this compound includes its benzodiazepine core, which is known for promoting a variety of biological effects. The combination of piperidine and fluorophenyl groups adds layers of structural diversity that may influence its pharmacological properties.
- Potential Therapeutic Applications: Compounds with similar structural motifs have been studied for their efficacy in treating various conditions, particularly in the realm of neurological disorders and cancer therapies. The presence of the benzimidazole framework is particularly interesting as it is often linked to anti-cancer activities.
- Fluorine Substitution: The inclusion of fluorine atoms in organic compounds is a notable feature. Fluorinated compounds can exhibit enhanced metabolic stability and greater binding affinity to biological targets. This can result in improved efficacy compared to their non-fluorinated counterparts.
- Research and Development: Ongoing research is likely to explore the biological activity of this compound. Scientists are keen to understand how its structural attributes relate to its function, paving the way for the design of novel pharmaceuticals.
To quote a famous chemist, "The beauty of chemistry lies in its capacity to unveil the complex ballet of atoms." This compound exemplifies that beauty and the intricate dance between structure and function within biological systems.
Ultimately, compounds like 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one are at the frontier of scientific discovery, holding the promise of new therapeutic strategies in the face of health challenges.
Synonyms
pimozide
2062-78-4
Opiran
Pimozidum
pimozida
McN-JR-6238
Pimozidum [INN-Latin]
Primozida
R 6238
Primozida [INN-Spanish]
CCRIS 9172
2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
NSC 170984
UNII-1HIZ4DL86F
EINECS 218-171-7
1HIZ4DL86F
NSC-170984
BRN 0729089
CHEBI:8212
1-(1-(4,4-Bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone
1-(4,4-Bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine
NSC170984
1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
R-623
5-24-02-00367 (Beilstein Handbook Reference)
Pimozide [USAN:USP:INN:BAN:JAN]
Pimozidum (INN-Latin)
Primozida (INN-Spanish)
PIMOZIDE (MART.)
PIMOZIDE [MART.]
PIMOZIDE (USP-RS)
PIMOZIDE [USP-RS]
1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
PIMOZIDE (EP MONOGRAPH)
PIMOZIDE [EP MONOGRAPH]
PIMOZIDE (USP MONOGRAPH)
PIMOZIDE [USP MONOGRAPH]
Pimozide (USAN:USP:INN:BAN:JAN)
1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
2H-BENZIMIDAZOL-2-ONE, 1-(1-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-4-PIPERIDINYL)-1,3-DIHYDRO
1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
1-(1-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-4-PIPERIDYL)-2-BENZIMIDAZOLINONE
1-(1-(4,4-Bis(4-fluorophenyl)butyl)piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one
N05AG02
218-171-7
Orap
R-6238
R6238
McN-JR 6238
3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
MFCD00055081
CHEMBL1423
MLS000028410
MLS002702058
DTXSID8023474
1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
NCGC00015802-08
NCGC00015802-18
SMR000058385
CAS-2062-78-4
R 623
DTXCID803474
Primozide
Pimozida [INN-Spanish]
3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1~{H}-benzimidazol-2-one
Orap (TN)
SR-01000075392
Pimozide?
1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one
Prestwick_395
Pimozide (Standard)
Spectrum_000445
Tocris-0937
PIMOZIDE [USAN]
PIMOZIDE [INN]
PIMOZIDE [JAN]
PIMOZIDE [MI]
PIMOZIDE [VANDF]
Opera_ID_1580
Prestwick0_000308
Prestwick1_000308
Prestwick2_000308
Prestwick3_000308
Spectrum2_001026
Spectrum3_001451
Spectrum4_000420
Spectrum5_001308
Lopac-P-1793
GTPL90
PIMOZIDE [WHO-DD]
NCIMech_000356
P 1793
Lopac0_000946
SCHEMBL41584
BSPBio_000276
BSPBio_001439
BSPBio_002941
KBioGR_000720
KBioSS_000925
MLS001077311
BIDD:GT0435
DivK1c_000386
SPECTRUM1501134
Pimozide (JP18/USP/INN)
SPBio_001211
SPBio_002495
PIMOZIDE [ORANGE BOOK]
BPBio1_000304
SCHEMBL7519553
BCBcMAP01_000043
HMS501D08
KBio1_000386
KBio2_000925
KBio2_003493
KBio2_006061
KBio3_002441
NINDS_000386
GLXC-06097
HMS1568N18
HMS1791H21
HMS1921H19
HMS1989H21
HMS2089C11
HMS2092F09
HMS2095N18
HMS2231P23
HMS3262N14
HMS3267E19
HMS3370N13
HMS3402H21
HMS3411J16
HMS3675J16
HMS3712N18
Pharmakon1600-01501134
DXC19357
Tox21_110224
Tox21_301586
Tox21_500946
BDBM50334150
CCG-35918
CCG-36461
CCG-39728
EX-A10246
HY-12987R
NSC757854
s4358
2-Benzimidazolinone, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one
AKOS024458706
Tox21_110224_1
DB01100
FP63878
LP00946
NSC-757854
SDCCGSBI-0050920.P004
IDI1_000386
SMP1_000241
NCGC00015802-01
NCGC00015802-02
NCGC00015802-03
NCGC00015802-04
NCGC00015802-05
NCGC00015802-06
NCGC00015802-07
NCGC00015802-09
NCGC00015802-10
NCGC00015802-11
NCGC00015802-12
NCGC00015802-13
NCGC00015802-14
NCGC00015802-15
NCGC00015802-16
NCGC00015802-26
NCGC00015802-29
NCGC00016601-01
NCGC00022282-03
NCGC00024888-01
NCGC00024888-02
NCGC00024888-03
NCGC00024888-04
NCGC00024888-05
NCGC00024888-06
NCGC00024888-07
NCGC00255294-01
NCGC00261631-01
AS-13916
DA-56876
HY-12987
SBI-0050920.P003
AB00052215
CS-0012921
EU-0100946
NS00003971
SW196639-3
C07566
D00560
EN300-127038
F70142
AB00052215-06
AB00052215_07
AB00052215_08
L000494
Q144085
WLN: T56 BMVNJ D- DT6NTJ A3YR DF&R DF
SR-01000075392-1
SR-01000075392-3
SR-01000075392-4
SR-01000075392-6
BRD-K01292756-001-06-0
BRD-K01292756-001-13-6
BRD-K01292756-001-23-5
BRD-K01292756-001-24-3
BRD-K01292756-001-25-0
Pimozide, European Pharmacopoeia (EP) Reference Standard
2-Benzimidazolinone,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine
Pimozide, United States Pharmacopeia (USP) Reference Standard
1-[1-[4,4-Bis(p-flurophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2h-benzimidazole-2-one
1-{1-[4,4-bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
2H-Benzimidazol-2-one,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)
Pimozide (1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidaol-2-one)
PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
Solubility of 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one
The solubility of the compound 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one is influenced by several factors, including its molecular structure and the presence of functional groups. Understanding its solubility can provide valuable insights into its potential applications.
Key Points about Solubility:
In summary, the solubility of 3-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidyl]-1H-benzimidazol-2-one necessitates careful consideration of the solvent environment, temperature conditions, and pH. As always, empirical testing is recommended for precise solubility data in relevant conditions.