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Nifuroxazide

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Identification
Molecular formula
C12H10N4O5S
CAS number
965-52-6
IUPAC name
3-[1-[5-methyl-3-(5-nitro-2-furyl)isoxazol-4-yl]ethylideneamino]isothiourea
State
State

At room temperature, nifuroxazide is a solid. It is often used in powdered form for various applications.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
275.24g/mol
Molar mass
275.2370g/mol
Density
1.5400g/cm3
Appearence

Nifuroxazide typically appears as a yellow crystalline powder. Its bright color makes it visually distinctive.

Comment on solubility

Solubility Properties of 3-[1-[5-methyl-3-(5-nitro-2-furyl)isoxazol-4-yl]ethylideneamino]isothiourea

The compound 3-[1-[5-methyl-3-(5-nitro-2-furyl)isoxazol-4-yl]ethylideneamino]isothiourea demonstrates intriguing solubility characteristics which are vital for its applications in various chemical and biological settings.

Factors Influencing Solubility

  • Polarity: The presence of functional groups such as isoxazole and isothiourea indicates that the compound may exhibit varying degrees of polarity, affecting its solubility in different solvents.
  • Hydrogen Bonding: The capability of forming hydrogen bonds can enhance solubility in polar solvents like water, while non-polar solvents may not effectively dissolve the compound.
  • Molecular Size: The relatively complex structure of this compound could also impede solubility due to steric hindrance, which might limit its interaction with solvent molecules.

Expected Solubility

In general, compounds that contain nitro and amino groups tend to be more soluble in polar solvents. Thus, it can be anticipated that:

  • This compound is likely to exhibit some degree of solubility in water and other polar solvents.
  • It may have limited solubility in non-polar solvents, reflecting its structural characteristics.

The solubility of 3-[1-[5-methyl-3-(5-nitro-2-furyl)isoxazol-4-yl]ethylideneamino]isothiourea is crucial for its practical applications, and understanding these properties will enhance its utilization in research and industry.

Interesting facts

Interesting Facts about 3-[1-[5-methyl-3-(5-nitro-2-furyl)isoxazol-4-yl]ethylideneamino]isothiourea

This complex molecule represents an intriguing subject of study in the realm of medicinal chemistry and organic synthesis. Here are a few fascinating aspects of this compound:

  • Antimicrobial Activity: Compounds similar to this structure have shown promising antimicrobial properties, making them potential candidates for developing new antibiotics.
  • Unique Functional Groups: The incorporation of isothiourea and isoxazole moieties in its structure offers unique chemical reactivity, which can be exploited in various synthetic applications.
  • Structure-Activity Relationship (SAR): Researchers are particularly interested in how modifications in the molecular structure impact biological activity, shedding light on effective drug design.
  • Di-functional Nature: The dual functional groups within this compound allow for versatile chemical modifications, making it valuable in drug discovery for developing tailored therapeutic agents.
  • Potential Applications: Beyond its medicinal prospects, this compound could have applications in agrochemicals and materials science due to its reactivity.

"The journey of a compound from synthesis to application is a fascinating exploration of chemistry's vast landscape." As students and researchers delve deeper into compounds like this one, they uncover the interconnections between structure, function, and innovation.

This compound illustrates the rich diversity and potential within organic chemistry, inviting further investigation and exploration in both laboratory settings and practical applications.