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Gacyclidine

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Identification
Molecular formula
C25H25NO2
CAS number
60547-90-4
IUPAC name
3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione
State
State

At room temperature, gacyclidine is in a solid state. It is stable under normal conditions but is typically stored in a cool, dry place to preserve its integrity.

Melting point (Celsius)
181.50
Melting point (Kelvin)
454.65
Boiling point (Celsius)
545.15
Boiling point (Kelvin)
818.30
General information
Molecular weight
406.48g/mol
Molar mass
406.5000g/mol
Density
1.2273g/cm3
Appearence

Gacyclidine appears as a crystalline solid. It is typically an off-white to pale beige color, reflecting its purity and crystalline structure.

Comment on solubility

Solubility of 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione

The solubility of 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione is a topic that merits attention due to its unique structural characteristics. Understanding its solubility behavior is crucial for practical applications in pharmaceutical formulations, as well as for predicting its behavior in biological systems.

Factors Influencing Solubility

Several key factors contribute to the solubility of this compound:

  • Polarity: The presence of polar functional groups can increase solubility in polar solvents.
  • Molecular Weight: Higher molecular weights often correlate with lower solubility in certain solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in aqueous environments.
  • Temperature: An increase in temperature can often improve solubility for many organic compounds.

General Solubility Insights

While specific solubility data for 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione may not be readily available, we can predict some trends based on similar compounds:

  • Solvent Compatibility: It is likely to exhibit good solubility in organic solvents such as DMSO or ethanol.
  • Aqueous Solubility: Its solubility in water may be limited due to hydrophobic characteristics imparted by the aromatic rings.

In conclusion, the solubility of 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione is influenced by its structural properties. Further empirical studies are essential to optimize solubility for therapeutic purposes, allowing researchers to effectively harness its potential benefits.

Interesting facts

Interesting Facts About 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione

This compound, recognized for its complex structure, belongs to a class of chemical entities known as piperidines. Here are some captivating points surrounding this intriguing molecule:

  • Pharmacological Potential: Compounds with a piperidine backbone, like this one, often exhibit noteworthy pharmacological properties, making them subjects of interest in medicinal chemistry.
  • Structural Versatility: The substitution patterns present in this compound allow for diverse interactions with biological targets, leading to potential therapeutic applications.
  • Research Applications: The unique arrangement of the piperidine and phenyl groups may influence its ability to cross the blood-brain barrier, bringing it to the attention of neuroscientists studying central nervous system pharmacology.
  • Synthetic Challenges: The synthesis of such compounds is often complex and requires advanced techniques, which can serve as an excellent practical exercise for students delving into organic synthesis.

In summary, 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione offers a fascinating glimpse into the world of chemical research, especially in the realms of pharmacology and synthetic chemistry. Its multifaceted nature paves the way for further examination and potential discoveries.

Synonyms
Benzetimide
14051-33-3
Benzetimidum
Benzetimide [INN]
Benzezimida
Spasmental
Benzetimide (INN)
(+-)-Benzetimide
bencetimida
Benzetimidum [INN-Latin]
Benzezimida [INN-Spanish]
UNII-B987T0L5FX
2-(1-Benzyl-4-piperidyl)-2-phenylglutarimide
B987T0L5FX
119391-55-8
DTXSID2046173
2-[1-BENZYL-4-PIPERIDYL]-2-PHENYLGLUTARIMIDE
BENZETIMIDE [MI]
Spasmental [veterinary] (TN)
DTXCID0026173
(RS)-3-(1-Benzyl-4-piperidyl)-3-phenyl-2,6-piperidindion
(3,4'-Bipiperidine)-2,6-dione, 3-phenyl-1'-(phenylmethyl)-
Benzetimidum (INN-Latin)
Benzezimida (INN-Spanish)
Spasmental (veterinary)
3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione
CHEMBL10272
(+/-)-Benzetimide
3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione
NCGC00160474-01
Dextrobenzetimide
()-Benzetimide
[3,4'-Bipiperidine]-2,6-dione,3-phenyl-1'-(phenylmethyl)-
1''-Benzyl-3-phenyl-[3,4'']bipiperidinyl-2,6-dione
SCHEMBL148330
1'-Benzyl-3-phenyl-[3,4'-bipiperidine]-2,6-dione
CHEBI:188883
LQQIVYSCPWCSSD-UHFFFAOYSA-N
EX-A3066
WAA88899
Tox21_111838
BDBM50018556
AKOS005066173
NCGC00160474-02
DA-61576
CAS-14051-33-3
EU-0015149
NS00007939
NS00100852
D07513
L001340
Q27274534
(+)-1''-benzyl-3-phenyl-3,4''-bipiperidine-2,6-dione
(-)-1''-benzyl-3-phenyl-3,4''-bipiperidine-2,6-dione
(+/-)-1''-benzyl-3-phenyl-3,4''-bipiperidine-2,6-dione
Dexetimide1''-Benzyl-3-phenyl-[3,4'']bipiperidinyl-2,6-dione