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Benzydamine

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Identification
Molecular formula
C19H23NO2
CAS number
745-13-3
IUPAC name
3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole
State
State

At room temperature, Benzydamine exists as a solid.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
470.15
Boiling point (Kelvin)
743.30
General information
Molecular weight
309.42g/mol
Molar mass
309.4230g/mol
Density
0.9900g/cm3
Appearence

Benzydamine is typically found as a white crystalline powder. It is known for being odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole

The solubility of 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole can be an intriguing subject due to its unique chemical structure. Understanding its solubility profile is crucial for various applications, especially in pharmaceutical formulations.

Generally, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the 5-methoxy group may enhance non-polar interactions, potentially affecting solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds with solvents could increase its solubility in alcohols and acids.
  • Temperature: Like many organic compounds, the solubility of this indole derivative can vary significantly with temperature changes.

In practice, this compound might exhibit:

  • Higher solubility in organic solvents such as dichloromethane or ethanol.
  • Limited solubility in water, typical for many indole derivatives, making it crucial to devise appropriate delivery methods.

Therefore, while it is essential to conduct solubility tests for definitive results, one can hypothesize that the 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole is likely to be more soluble in non-polar organic solvents rather than in aqueous solutions. Ultimately, a proper understanding of its solubility can aid in the effective application of this compound in various chemical and pharmacological contexts.

Interesting facts

Interesting Facts about 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole

3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole is a fascinating chemical compound with intriguing properties and potential applications. Below are some engaging points worth noting:

  • Origin of the Name: The name of this compound reflects its structure, featuring an indole core, which is a common structural motif found in many biologically active molecules. The specific substitution patterns denote particular functional groups that can significantly alter the compound's properties.
  • Biological Relevance: Compounds related to indole often exhibit a wide range of biological activities. This particular compound is being studied for its potential therapeutic effects, including its influence on the central nervous system due to the piperidine moiety, which may enhance its pharmacological profile.
  • Pharmaceutical Potential: Researchers are actively investigating compounds like 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole for their potential use in treating various conditions, particularly in the realm of psychiatry, given the role that indole derivatives play in neurotransmitter systems.
  • Diverse Applications: Beyond medicinal chemistry, this compound’s unique structure could serve various functions in organic synthesis, acting as an intermediate for more complex organic compounds.
  • Structure-Activity Relationship (SAR): The intricate balance of functional groups in this compound makes it a prime candidate for studying the SAR, helping chemists understand how molecular changes can influence biological activity, which is crucial in drug development.

In summary, 3-[(1-benzyl-4-piperidyl)methyl]-5-methoxy-1H-indole is not just a simple chemical formula; it embodies a world of possibilities in medicine and beyond. The ongoing research surrounding such compounds continually opens new avenues for discovery, reminding us of the importance of chemical diversity in innovation.