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3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole chloride

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Identification
Molecular formula
C19H19BrClN2
CAS number
.null
IUPAC name
3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride
State
State

At room temperature, this compound is typically in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.00
General information
Molecular weight
421.75g/mol
Molar mass
421.7460g/mol
Density
1.5000g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. Its appearance might vary slightly based on purity and specific synthesis conditions.

Comment on solubility

Solubility of 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride

The solubility of the compound 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride is influenced by its unique chemical structure, which includes a quaternary ammonium moiety and an indole framework. Understanding its solubility characteristics can provide insights into its potential applications and behavior in various environments.

Key Factors Affecting Solubility:

  • Polarity: The pyrrolidinium group contributes to the overall polarity of the molecule, increasing its solubility in polar solvents such as water.
  • Ionization: As a chloride salt, the compound is likely to dissociate in aqueous solutions, which can enhance its solubility compared to its neutral forms.
  • Temperature: Typically, the solubility of salts increases with temperature; therefore, elevated temperatures may facilitate the dissolution of this compound.
  • Solvent Type: The solubility behavior could vary significantly depending on the solvent used, with organic solvents potentially showcasing different results compared to water.

In the context of experimental work, it is essential to consider the solubility profile for aspects such as:

  • Formulation in drug delivery systems
  • Behavior in biological environments
  • Potential interactions with other compounds

In conclusion, the solubility of 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride is a complex interplay of its structural attributes and environmental conditions. In exploring these solubility characteristics, researchers can better tailor applications and predict the compound's behavior in various settings.

Interesting facts

Interesting Facts about 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride

This compound presents a fascinating combination of organic chemistry and medicinal potential, characterized by its unique structural motifs and implications in various fields.

Key Features

  • Benzylpyrrolidin-1-ium Structure: The presence of the benzylpyrrolidine unit adds considerable steric and electronic diversity, which can influence the compound's interaction with biological targets.
  • Bromo Substituent: The bromo group at the 5-position of the indole ring not only marks a point of reactivity but also enhances lipophilicity, potentially improving bioavailability in pharmaceutical applications.
  • Indole Moiety: Indoles are a class of compounds that have been extensively studied for their pharmacological properties, including roles in neurotransmission and as anticancer agents.

Researchers are particularly interested in the following aspects of this compound:

Applications and Research

  • Pharmaceutical Development: There is growing interest in compounds that feature indole structures due to their diverse biological activities, leading to ongoing research into their potential therapeutic properties.
  • Chemical Synthesis: The synthesis of this compound may involve innovative methodologies, particularly regarding the formation of the cationic pyrrolidine and the selective bromination of the indole.
  • Role in Neurochemistry: Some studies suggest that indole derivatives can modulate neurotransmitter systems, making compounds like this a subject of interest in understanding brain chemistry.

In conclusion, 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-bromo-1H-indole;chloride is a prime example of how intricate chemical design can lead to compounds with exciting properties and potential applications. As research progresses, we might find this compound playing a significant role in advancing our understanding of various biochemical processes and treatment methodologies.

Synonyms
3-(1-Benzyl-2-pyrrolidinyl)-5-bromoindole hydrochloride
19134-01-1
INDOLE, 3-(1-BENZYL-2-PYRROLIDINYL)-5-BROMO-, MONOHYDROCHLORIDE