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benzethidine hydrochloride

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Identification
Molecular formula
C18H20Cl2IN2
CAS number
942-86-7
IUPAC name
3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride
State
State

At room temperature, benzethidine hydrochloride is in a solid state. It typically remains stable under standard laboratory conditions when stored properly. Its stability can be compromised by exposure to light and air, which might alter its efficacy for certain applications.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
327.23g/mol
Molar mass
327.2300g/mol
Density
1.2800g/cm3
Appearence

Benzethidine hydrochloride appears as a white to off-white crystalline powder. It is generally odorless and has a bitter taste. The compound is hygroscopic, meaning it can absorb moisture from the air, which can affect its appearance over time.

Comment on solubility

Solubility of 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride

The solubility of 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride can be influenced by several factors, given its complex structure and ionic character. Here are some key points to consider:

  • Ionic Characteristics: Being a chloride salt, this compound is expected to exhibit significant solubility in polar solvents like water, as ionic compounds dissolve well in polar environments due to ion-dipole interactions.
  • Hydrophilicity/Hydrophobicity: The presence of the benzyl group adds a hydrophobic character to the molecule, which may limit its overall solubility. Compounds with larger hydrophobic regions typically show decreased solubility in water.
  • Temperature Influence: Solubility often increases with temperature; hence, heating the solvent might enhance the solubility of this compound.
  • pH Dependency: As an ionic compound, its solubility could also be affected by the pH of the solution, especially if it involves protonation or deprotonation of functional groups.

In summary, while 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride is expected to be soluble in water due to its ionic nature, the overall extent of solubility can be markedly influenced by its molecular structure and the conditions under which it is dissolved. Testing in various solvents may yield additional insights into its solubility behavior.

Interesting facts

3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride

This fascinating compound, known for its complex structure and interesting properties, is part of a class of molecules that engages chemists and researchers alike. Here are some intriguing aspects to consider:

  • Unique Structure: The presence of the 1-benzylpyrrolidin-1-ium moiety is noteworthy as it contributes to the compound's stability and potential reactivity. Pyrrolidine rings are known for their role in various biological systems.
  • Chlorine Substitution: The chlorine atom in the structure can significantly influence the compound's reactivity and the biological activities it may exhibit, making it a subject of interest in medicinal chemistry.
  • Indole Unit: The indole scaffold is a prevalent structure in many natural compounds and pharmaceuticals. Indoles have been studied for their diverse biological properties, including their roles as antidepressants, anti-inflammatory agents, and more.
  • Potential Applications: Given its unique structural features, this compound might hold potential in drug development, particularly in areas like neurology and psychiatry due to its influence on neurotransmitter systems.

In the words of famous chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." As researchers continue to explore compounds like 3-(1-benzylpyrrolidin-1-ium-2-yl)-5-chloro-1H-indole;chloride, they may uncover novel therapeutic avenues that benefit human health. The journey of discovery in chemistry is ever-evolving, and each compound holds the potential for groundbreaking insights.

Synonyms
3-(1-Benzyl-2-pyrrolidinyl)-5-chloroindole hydrochloride
19134-02-2
INDOLE, 3-(1-BENZYL-2-PYRROLIDINYL)-5-CHLORO-, MONOHYDROCHLORIDE