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Identification
Molecular formula
C19H20N2
CAS number
50818-87-6
IUPAC name
3-(1-benzylpyrrolidin-2-yl)-1H-indole
State
State

This compound is typically a solid at room temperature, often appearing as crystalline due to its structured aromatic nature.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
443.00
Boiling point (Kelvin)
716.15
General information
Molecular weight
288.39g/mol
Molar mass
288.3890g/mol
Density
1.1950g/cm3
Appearence

The compound 3-(1-benzylpyrrolidin-2-yl)-1H-indole typically appears as a crystalline solid. It is characterized by its distinct aromatic and heterocyclic indole motif, contributing to its solid state under standard conditions.

Comment on solubility

Solubility of 3-(1-benzylpyrrolidin-2-yl)-1H-indole

The solubility of 3-(1-benzylpyrrolidin-2-yl)-1H-indole is an intriguing aspect of its chemical properties. Understanding the solubility of this compound involves considering several factors that can influence its behavior in different solvents:

  • Polarity: The presence of various functional groups in the molecule dictates its polarity, which directly affects its solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The ability of the molecule to form hydrogen bonds can enhance solubility, especially in polar solvents like water.
  • Temperature: Generally, increasing temperature can increase the solubility of many organic compounds, although this can vary depending on the specific interactions present in the compound.

In practice, 3-(1-benzylpyrrolidin-2-yl)-1H-indole may show varying solubility profiles:

  1. In polar solvents, its solubility may be moderate due to the balance of hydrophilic and hydrophobic regions.
  2. In non-polar solvents, it could exhibit higher solubility owing to its aromatic structure which is compatible with non-polar environments.

As a result, the solubility of 3-(1-benzylpyrrolidin-2-yl)-1H-indole can be characterized as selective, favoring solvents that can accommodate its molecular attributes. Always consider conducting solubility tests in specific solvents to determine optimal conditions for use in practical applications.

Interesting facts

Interesting Facts About 3-(1-benzylpyrrolidin-2-yl)-1H-indole

3-(1-benzylpyrrolidin-2-yl)-1H-indole is a fascinating compound that has garnered attention in the fields of organic chemistry and pharmacology. Here are some intriguing points about this compound:

  • Structural Complexity: The compound features a unique structural framework integrating an indole ring with a substituted pyrrolidine. This complexity can lead to interesting interactions with biological targets.
  • Biological Relevance: Compounds of this nature are often investigated for their potential as drug candidates. They might exhibit activity against various biological pathways, possibly making them useful in treating neurological disorders.
  • Ligand Potential: Due to the presence of multiple functional groups, 3-(1-benzylpyrrolidin-2-yl)-1H-indole may act as a ligand for various receptors. Its binding affinity could provide critical insight into developing new therapeutic agents.
  • Synthetic Routes: The synthesis of this compound may involve several innovative techniques. Chemists often explore different methodologies to create such multi-functional molecules, which can enhance their versatility in applications.
  • Research Applications: This compound can serve as a valuable model for studying indole derivatives. Researchers might use it in assays to assess its pharmacological properties and mechanism of action.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." The exploration of compounds like 3-(1-benzylpyrrolidin-2-yl)-1H-indole exemplifies this spirit, as each investigation can yield new insights into the realms of chemistry and medicinal science.

The journey through the synthesis and study of this compound not only expands our knowledge base but also pushes the boundaries of what we understand about chemical interactions and pharmacology!

Synonyms
3-(1-benzylpyrrolidin-2-yl)-1H-indole
19137-96-3
3-(1-Benzyl-2-pyrrolidinyl)-1H-indole
BRN 0537893
3-(1-Benzyl-2-pyrrolidinyl)indole
INDOLE, 3-(1-BENZYL-2-PYRROLIDINYL)-
3-[1-(Phenylmethyl)pyrrolidin-2-yl]-1H-indole
DTXSID20940752
1-benzyl-2-(indol-3-yl)pyrrolidine