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3-(1-Benzylpyrrolidin-2-yl)-5-bromo-1H-indole

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Identification
Molecular formula
C19H19BrN2
CAS number
913255-83-1
IUPAC name
3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
353.27g/mol
Molar mass
353.2290g/mol
Density
1.4200g/cm3
Appearence

The compound typically appears as a solid. Specific details about its color or other physical characteristics may not be widely documented.

Comment on solubility

Solubility of 3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole

Understanding the solubility of 3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole is essential for its application in various chemical processes and pharmaceutical formulations. The solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of a bromine atom and the pyrrolidine group affects the overall polarity, which in turn influences solubility in polar vs. non-polar solvents.
  • Hydrophobic vs. Hydrophilic Characteristics: The indole moiety tends to be more hydrophobic, while the pyrrolidine ring may offer some hydrophilic character, potentially increasing solubility in certain solvent systems.
  • Temperature: As with many compounds, increasing temperature typically enhances solubility due to higher kinetic energy, which helps to overcome intermolecular forces.

Research indicates that 3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole is likely to dissolve effectively in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol, while its solubility in water may be limited. This characteristic is common among many indole derivatives, where hydrophobic interactions play a significant role.

In summary, the solubility profile of this compound is crucial for its utilization. As one chemist put it, "Understanding solubility is like understanding the language of your compound; it tells you how it will behave in different environments."

Interesting facts

Interesting Facts about 3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole

3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole, a fascinating compound, is known for its complex structure and potential applications in medicinal chemistry. Here are some captivating points regarding this intriguing chemical:

  • Biological Relevance: The indole moiety is a vital structure in many natural products and pharmaceuticals, playing a critical role in the activity of various biologically active compounds.
  • Integration of Components: The combination of a benzyl group and a pyrrolidine ring enhances its molecular diversity, which is often associated with improved pharmacological properties.
  • Research Interest: This compound has garnered attention in research due to its potential applications in the development of new therapeutic agents, particularly in the fields of neuropharmacology and psychiatry.
  • Versatile Synthesis: The synthesis of such compounds often involves multi-step procedures, showcasing the creativity and innovative approaches by chemists in material science.
  • Structure-Activity Relationship (SAR): Studying the SAR of this compound could reveal important insights into how small structural changes may influence its biological activity, guiding future drug design.
  • Safety Considerations: As with many synthetic compounds, understanding the toxicity and environmental impact is essential for the development and application of this molecule in medical settings.

Overall, 3-(1-benzylpyrrolidin-2-yl)-5-bromo-1H-indole illustrates the fascinating interplay between structure and function in medicinal chemistry. As researchers delve deeper into its properties, we may uncover even more about its potential uses in improving human health.