3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole

Identification

Molecular formula

C₂₀H₂₄N₂

CAS number

.Unknown

IUPAC name

3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole

State

At room temperature, 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole is most often found in a solid state.

Melting point (Celsius)

132.00

Melting point (Kelvin)

405.15

Boiling point (Celsius)

434.00

Boiling point (Kelvin)

707.15

General information

Molecular weight

322.45g/mol

Molar mass

322.4480g/mol

Density

1.1560g/cm³

Appearence

3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole typically presents as a solid crystalline substance. The color can vary based on purity and method of synthesis, but it is generally white to off-white.

Comment on solubility

Solubility of 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole

The solubility of 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole can be quite intriguing given its structural characteristics.

Factors Influencing Solubility

Several factors can affect the solubility of this compound:

Polarity: The presence of both the pyrrolidine and indole moieties can influence the overall polarity. Polar compounds typically have greater solubility in polar solvents, while non-polar compounds prefer non-polar environments.
Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvent molecules can enhance solubility in certain solvents, especially alcohols and water.
Temperature: Increasing temperature often increases solubility of solids in liquids due to enhanced molecular movement.
pH: The ionization state of the compound can shift with changes in pH, possibly affecting solubility.

Typical Solvents

Based on its organic structure, you might expect:

Higher solubility in organic solvents such as ethanol, DMSO (Dimethyl sulfoxide), or dimethylformamide (DMF).
Limited solubility in polar solvents like water, due to its relatively hydrophobic characteristics.

In conclusion, the solubility of 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole exhibits a complex interplay of structural and environmental factors, making it a fascinating subject for further study.

Interesting facts

Interesting Facts about 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole

3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole is a fascinating compound that belongs to the indole family, which is well-known for its significant presence in a variety of biological systems and pharmacological agents. Here are some intriguing insights into this compound:

Indole Derivative: Indoles are important in medicinal chemistry and can be found in many natural products, including tryptophan and various alkaloids.
Biological Relevance: Compounds related to indole have been researched for their potential roles in neurobiology and as antidepressants, which adds to the interest in this specific compound.
Pyrrolidine Incorporation: The pyrrolidine moiety in this compound contributes to its structural diversity and potential activity. Pyrrolidines are often found in active pharmaceutical ingredients (APIs), making them valuable in drug design.
Potential Applications: Given the structure, one could explore its role in various fields such as medicinal chemistry, neuroscience, and synthetic organic chemistry, as modifications can lead to enhanced biological activity.
Structure-Activity Relationships: The unique combination of the benzyl group and the methyl substitution on the indole structure provides an opportunity to study how these changes affect the compound's biochemical properties.

As a compound of interest in research, 3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole represents the intersection of organic chemistry and biological activity. Understanding its properties can pave the way for novel therapeutic approaches and enhance our knowledge of chemical interactions within biological systems.

Synonyms

3-(1-Benzyl-2-pyrrolidinyl)-7-methylindole

19133-99-4

BRN 0546110

INDOLE, 3-(1-BENZYL-2-PYRROLIDINYL)-7-METHYL-

3-(1-benzylpyrrolidin-2-yl)-7-methyl-1H-indole

DTXSID60940731