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3-(1-Ethyl-5,5-dimethylpyrrolidin-2-yl)-1H-indole

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Identification
Molecular formula
C16H22N2
CAS number
13462-32-3
IUPAC name
3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
353.00
Boiling point (Kelvin)
626.15
General information
Molecular weight
240.36g/mol
Molar mass
240.3610g/mol
Density
1.1200g/cm3
Appearence

The compound is typically found as a solid. It may appear as a crystalline substance, often exhibiting a white to off-white color.

Comment on solubility

Solubility of 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole

The solubility of 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole in various solvents is an interesting topic due to its complex molecular structure.

Key Factors Affecting Solubility:

  • Molecular Structure: The presence of the pyrrolidine ring contributes to the overall solubility, as nitrogen atoms can form hydrogen bonds.
  • Polarity: The combination of polar and nonpolar functional groups in the molecule influences its interaction with solvents.
  • Hydrogen Bonding: The ability of the compound to act as both a hydrogen bond donor and acceptor affects its solubility profile.

As a general observation, compounds similar to 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole tend to exhibit:

  • Limited solubility in water due to their hydrophobic characteristics.
  • Higher solubility in organic solvents such as ethanol, methanol, and acetonitrile.
  • Potential to form amorphous solids, which can enhance solubility compared to their crystalline counterparts.

Overall, understanding the solubility of this compound is crucial, as it affects its bioavailability, stability, and application in various fields. As observed, "solubility is not just a property; it’s a gateway to understanding how compounds interact in different environments.”

Interesting facts

Interesting Facts about 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole

The compound 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole belongs to a fascinating class of organic compounds known for their complex structures and significant biological activity. Here are some noteworthy aspects:

  • Structural Intrigue: The compound features a unique interconnection between an indole and a pyrrolidine moiety, creating a structure that is both versatile and interesting for medicinal chemistry.
  • Biological Relevance: Indole derivatives are widely recognized for their roles in various biological processes. They are often the foundation of numerous pharmaceuticals and can exhibit diverse biological activities, including anti-inflammatory, analgesic, and antitumor effects.
  • Research Opportunities: Due to their complex nature, compounds like this offer exciting opportunities for drug discovery in fields such as neuroscience and oncology. Such compounds are commonly investigated for their potential to interact with various biological targets, including receptors and enzymes.
  • Potential Applications: The presence of the pyrrolidine group might impart interesting pharmacokinetic properties, enabling exploration in therapeutic areas such as mental health and cognitive enhancement.
  • Inspiring Nature: The indole nucleus is a key scaffold in many natural products, including the neurotransmitter serotonin, showcasing the intrinsic links between chemical structure and biological function.
  • Contemporary Studies: Current research often focuses on the synthesis of analogs of this compound to investigate their structure-activity relationships, further expanding our understanding of its potential applications in medicine.

To quote a famous chemist: "Molecules are the foundations of life. They can open doors to new therapies, creating a world where science and medicine intertwine seamlessly." This encapsulates the importance of studying compounds like 3-(1-ethyl-5,5-dimethyl-pyrrolidin-2-yl)-1H-indole, as they may hold the keys to future medical breakthroughs.

Synonyms
3-(1-ethyl-5,5-dimethylpyrrolidin-2-yl)-1H-indole
19137-79-2
3-(1-Ethyl-5,5-dimethyl-2-pyrrolidinyl)-1H-indole
BRN 0523024
3-(5,5-Dimethyl-1-ethyl-2-pyrrolidinyl)indole
INDOLE, 3-(5,5-DIMETHYL-1-ETHYL-2-PYRROLIDINYL)-
DTXSID50940745