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Indolizidine derivative chloride

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Identification
Molecular formula
C14H19ClN2
CAS number
141317-57-1
IUPAC name
3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride
State
State

This compound is typically found as a solid at room temperature. It is stable under standard conditions, but may require specific storage conditions to prevent degradation or moisture absorption.

Melting point (Celsius)
98.50
Melting point (Kelvin)
371.65
Boiling point (Celsius)
255.80
Boiling point (Kelvin)
528.95
General information
Molecular weight
248.76g/mol
Molar mass
248.7560g/mol
Density
1.1527g/cm3
Appearence

The compound appears as a crystalline solid that can range from off-white to light beige in color. It may also appear as a powder or in small aggregates, depending on the specific crystallization and preparation method used.

Comment on solubility

Solubility of 3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride

The solubility of 3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride can be quite interesting and reflects the compound's unique structure. Being a quaternary ammonium salt, the solubility properties are primarily dictated by its ionic character.

Here are some key points regarding its solubility:

  • Aqueous Solubility: This compound is expected to have good solubility in water due to the presence of the positively charged +N center, which attracts water molecules.
  • Polar Solvents: The solubility in polar solvents such as ethanol and methanol is likely to be high, driven by similar polar interactions.
  • Non-polar Solvents: Conversely, the solubility in non-polar solvents (like hexane or benzene) would be quite limited. This illustrates the classic principle that "like dissolves like."
  • Influence of Temperature: Solubility may also be influenced by temperature; generally, increased temperatures can enhance solubility in polar solvents.

Overall, the solubility characteristics of 3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride demonstrate a strong interaction with polar environments while resisting solvation in non-polar media. As a rule of thumb, understanding solubility is crucial for predicting the behavior and reactivity of chemical compounds in various formulations.

Interesting facts

Interesting Facts about 3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride

3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride is a fascinating compound that combines elements of both medicinal chemistry and organic synthesis. Here are some intriguing insights about this compound:

  • Quaternary Ammonium Structure: This compound features a quaternary ammonium structure, resulting from the presence of the pyrrolidin-1-ium group. This structural aspect is significant as it can enhance solubility and biological activity.
  • Pharmacological Potential: Indole derivatives, such as this compound, are known for their diverse pharmacological properties. They have been studied for their potential effects on the central nervous system, making them a point of interest in drug development.
  • Role in Neurotransmission: The presence of the indole ring lends itself to interaction with neurotransmitter receptors. Compounds containing this structure can mimic natural neurotransmitters, allowing for modulation of synaptic activity.
  • Research Applications: This compound may serve as a valuable tool in neuroscience research, helping to elucidate the mechanisms of neurotransmitter action and the development of new therapeutic strategies for neurological disorders.
  • Synthetic Pathways: The synthesis of such complex organic molecules often involves advanced techniques such as multiple-step synthesis and functional group manipulation, making it a subject of study for aspiring organic chemists.

In conclusion, 3-(1-ethylpyrrolidin-1-ium-2-yl)-1H-indole;chloride is more than just a chemical entity; it represents a broader interest in drug discovery and the exploration of compounds that can influence biological systems. The continual study of similar compounds not only enhances our understanding of chemistry but also opens avenues for medical breakthroughs.

Synonyms
3-(1-Ethyl-2-pyrrolidinyl)indole hydrochloride
19137-90-7
INDOLE, 3-(1-ETHYL-2-PYRROLIDINYL)-, MONOHYDROCHLORIDE