Skip to main content

Nicotine

ADVERTISEMENT
Identification
Molecular formula
C10H14N2
CAS number
54-11-5
IUPAC name
3-(1-ethylpyrrolidin-2-yl)-1H-indole
State
State

At room temperature, nicotine is typically a liquid. In its pure form, it is a clear-to-yellowish, oily liquid and is very hygroscopic.

Melting point (Celsius)
-79.00
Melting point (Kelvin)
194.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
162.24g/mol
Molar mass
162.2350g/mol
Density
1.0100g/cm3
Appearence

Nicotine is generally a colorless to pale yellow liquid. It is known for its oily texture and can become brown upon exposure to air or light due to oxidation. When pure, the compound is clear but can become discolored over time.

Comment on solubility

Solubility of 3-(1-ethylpyrrolidin-2-yl)-1H-indole

The solubility of 3-(1-ethylpyrrolidin-2-yl)-1H-indole in various solvents is a subject of interest due to its potential applications in pharmacology and materials science. Here are some key points regarding its solubility:

  • The compound is generally considered to have a moderate solubility in polar organic solvents such as ethanol and methanol.
  • In non-polar solvents like hexane or toluene, the solubility may be significantly lower due to the hydrophobic nature of the indole structure.
  • The presence of the pyrrolidine ring can enhance solubility in certain environments, particularly in biological systems where lipophilicity plays an important role.

In many cases, the solubility can be influenced by factors such as temperature and the presence of other solutes. As a rule of thumb, "like dissolves like"; therefore, when formulating solutions or considering interfaces in reactions, it is crucial to select solvents that closely match the polarity of the compound.

Overall, understanding the solubility properties of 3-(1-ethylpyrrolidin-2-yl)-1H-indole is essential for optimizing its formulation and application in various fields.

Interesting facts

Fascinating Insights into 3-(1-ethylpyrrolidin-2-yl)-1H-indole

3-(1-ethylpyrrolidin-2-yl)-1H-indole is a compound that has garnered attention in both the fields of medicinal chemistry and neuroscience. Here are some intriguing details about this compound:

  • Structural Complexity: This compound features a unique hybrid structure that showcases the combination of an indole nucleus with a pyrrolidine moiety, leading to interesting interactions with biological targets.
  • Potential Biological Activities: Indoles are often associated with various pharmacological properties, and research has indicated that derivatives like 3-(1-ethylpyrrolidin-2-yl)-1H-indole might exhibit antidepressant and anxiolytic effects. These properties make it a valuable subject of study in drug development.
  • Neuropharmacology: Given the indole’s connection to serotonin, compounds in this family are of significant interest for their interaction with neurotransmitter systems, especially in relation to mood regulation and cognitive function.
  • Synthetic Routes: The synthesis of this compound may involve several intriguing steps, often employing diverse organic reactions, which could include cyclization and alkylation processes, making it a delight for synthetic chemists.
  • Research Implications: With ongoing studies in the realm of neurology and pharmacology, understanding the complete spectrum of pharmacodynamic and pharmacokinetic properties of this compound could pave the way for innovative therapeutic approaches.

As researchers continue to explore the depths of this compound, its role in enhancing mental health and treating various neurological disorders makes it a hot topic in contemporary scientific discourse.

In summary, the journey of 3-(1-ethylpyrrolidin-2-yl)-1H-indole is one that intertwines the complexities of chemical structure with the promise of advancing medicinal science.

Synonyms
3-(1-ethylpyrrolidin-2-yl)-1H-indole
694425-25-7
DB-279281
1H-INDOLE, 3-(1-ETHYL-2-PYRROLIDINYL)-