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Norepinephrine

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Identification
Molecular formula
C8H11NO3
CAS number
51-41-2
IUPAC name
3-[1-hydroxy-2-(isopropylamino)ethyl]phenol
State
State

At room temperature, norepinephrine exists as a solid. It is typically found in a crystalline powder form. It is stable under normal conditions but should be stored away from light and moisture to prevent degradation.

Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
228.00
Boiling point (Kelvin)
501.15
General information
Molecular weight
169.18g/mol
Molar mass
169.1800g/mol
Density
1.2980g/cm3
Appearence

Norepinephrine, in its pure form, is a white to off-white crystalline powder. It is hygroscopic, meaning it readily absorbs moisture from the environment.

Comment on solubility

Solubility of 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol

The compound 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol, with its complex structure, exhibits interesting solubility characteristics. It is known for being soluble in various solvents, which can be influenced by several factors:

  • Polarity: The presence of hydroxyl groups increases the polarity of the compound, making it more soluble in polar solvents such as water and ethanol.
  • Temperature: Solubility often increases with temperature. Therefore, heating the solvent can enhance the dissolution process.
  • pH Levels: The ionization of the amine group can also affect solubility. At different pH levels, the compound may exist in ionized or unionized forms, thus influencing solubility in aqueous solutions.

As a general observation, 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol is likely to be more soluble in alkaline solutions due to the potential for protonation of the amine group, making it easier to interact with water molecules.

In summary, the solubility of this compound is a multifactorial phenomenon, largely dictated by its chemical structure and the nature of the solvent involved. Always consider these factors when evaluating solubility for practical applications.

Interesting facts

Interesting Facts about 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol

This fascinating compound, known as 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol, presents a unique structure that has interesting applications in various fields of chemistry and biology. Here are some notable aspects:

  • Synthetic Utility: It serves as a precursor in the synthesis of various pharmaceuticals, particularly in the development of analgesics and anti-inflammatory agents.
  • Biological Activity: Exhibiting potential biological activity, this compound is often studied for its interactions at the cellular level, particularly in the context of neurotransmitter modulation.
  • Structure-Activity Relationship: The presence of the hydroxy group and the isopropylamino functionality allows researchers to explore the compound's variance in biological responses, illustrating the importance of molecular architecture in drug design.
  • Research Significance: Due to its intriguing properties, it has garnered attention in medicinal chemistry studies, contributing to our understanding of how certain compounds can influence biochemical pathways.

Furthermore, this compound is a great example of how small structural changes can lead to diverse biological effects. As quoted by chemist Sir Derek Barton, "The structure of a substance is the essence of its identity," which profoundly emphasizes the importance of understanding the nuances of compounds like this.

In conclusion, 3-[1-hydroxy-2-(isopropylamino)ethyl]phenol not only showcases the beauty of chemical diversity but also serves as a crucial element in the pursuit of new therapeutic agents.

Synonyms
Metaterol
3571-71-9
Metaterol [INN]
KBU4V9QUHY
3-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenol
3-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol
Isopropylnoradrianol
Metaterolum [Latin]
Metaterolum
Metaterolum [INN-Latin]
Benzenemethanol, 3-hydroxy-alpha-(((1-methylethyl)amino)methyl)- (9CI)
EINECS 222-678-9
UNII-KBU4V9QUHY
BRN 2805325
m-Hydroxy-alpha-(isopropylaminomethyl)benzyl alcohol
3-Hydroxy-alpha-((isopropylamino)methyl)benzylalkohol
S 40045-9
Benzenemethanol, 3-hydroxy-alpha-(((1-methylethyl)amino)methyl)-
4-13-00-02654 (Beilstein Handbook Reference)
SCHEMBL249460
CHEMBL327122
m-Hydroxy-alpha-((isopropylamino)methyl)benzyl alcohol
BDBM92679
DTXSID10863209
LVISWIXSNZQRHA-UHFFFAOYSA-N
BENZYL ALCOHOL, m-HYDROXY-alpha-((ISOPROPYLAMINO)METHYL)-
AKOS006273701
DA-75436
HY-128515
1-(3-hydroxyphenyl)-2-isopropylaminoethanol
CS-0095019
NS00049204
EN300-4274955
Q6823271
3-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 7
Z1198155517
benzene, 1-hydroxy-3-(1-hydroxy-2-isopropylamino)ethyl-
M-HYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL