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Dopamine

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Identification
Molecular formula
C8H11NO2
CAS number
51-61-6
IUPAC name
3-[1-hydroxy-2-(methylamino)propyl]phenol
State
State

At room temperature, dopamine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
277.00
Boiling point (Kelvin)
550.15
General information
Molecular weight
153.18g/mol
Molar mass
153.1790g/mol
Density
1.2600g/cm3
Appearence

Dopamine appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 3-[1-hydroxy-2-(methylamino)propyl]phenol

The solubility of 3-[1-hydroxy-2-(methylamino)propyl]phenol is influenced by its unique chemical structure, which consists of both hydrophilic and hydrophobic components.

  • Hydrophilic interactions: The presence of the -OH (hydroxyl) group contributes to its potential solubility in polar solvents, such as water. The ability to form hydrogen bonds enhances its affinity for water, making it more soluble.
  • Hydrophobic interactions: On the other hand, the phenolic part of the compound may exhibit hydrophobic characteristics, which can decrease solubility in polar environments.
  • pH Dependency: The solubility may also vary with pH due to the ionization of the -NH2 (amino) group, potentially increasing solubility in alkaline conditions, where the amine can become protonated.

Overall, while 3-[1-hydroxy-2-(methylamino)propyl]phenol exhibits a degree of solubility in aqueous solutions, it is important to assess specific conditions, such as temperature and pH, for a complete understanding of its solubility profile. As the well-known saying goes, “Like dissolves like,” which means the balance of polar and non-polar characteristics will ultimately dictate its behavior in different solvents.

Interesting facts

Interesting Facts about 3-[1-hydroxy-2-(methylamino)propyl]phenol

This compound, also known as methylamino phenol, is fascinating not only due to its chemical structure but also because of its diverse applications in various fields. Here are some notable points regarding its significance:

  • Biological Significance: Compounds of this type often exhibit biological activity, making them valuable in pharmaceutical research. They can influence neurotransmitter systems, thus holding potential in the treatment of various neurological disorders.
  • Synthesis Routes: The synthesis of 3-[1-hydroxy-2-(methylamino)propyl]phenol involves several interesting chemical transformations. It can be synthesized through nucleophilic substitution methods and may require specific catalytic conditions, highlighting the intricate nature of organic chemistry.
  • Structure-Activity Relationship: Examining the structure of this compound reveals how modifications to alkyl groups can significantly alter its interaction with biological targets. This aspect is crucial for medicinal chemists aiming to enhance efficacy while reducing side effects.
  • Research Developments: Ongoing studies are delving into its potential as a precursor for more complex organic molecules. It serves as a scaffold for designing analogs that could lead to breakthrough therapies in drug development.
  • Environmental Impact: Analogous compounds are often scrutinized in environmental chemistry. Understanding their behavior and degradation in natural systems is essential for assessing their ecological footprint.

In summary, 3-[1-hydroxy-2-(methylamino)propyl]phenol is more than just a chemical compound; it embodies a wealth of research opportunities and applications that highlight the dynamic interplay between chemistry and biology. Its impact stretches from laboratory research to potential real-world applications, showcasing the importance of understanding such compounds in modern science.

Synonyms
3-Hydroxyephedrine
3002-40-2
m-Oxy-ephedrin
m-Oxy-ephedrin [German]
11C-hydroxyephedrine-meta
m-Hydroxy-alpha-(1-(methylamino)ethyl)benzyl alcohol
Benzenemethanol, 3-hydroxy-alpha-(1-(methylamino)ethyl)-, (R*,S*)-
BENZYL ALCOHOL, m-HYDROXY-alpha-(1-(METHYLAMINO)ETHYL)-
meta-hydroxyephedrine
11C-meta-Hydroxyephedrine
Benzenemethanol, 3-hydroxy-alpha-(1-(methylamino)ethyl)-, (R*,S*)-(9CI)
3-[1-hydroxy-2-(methylamino)propyl]phenol
DTXSID20952431
AKOS040749953