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3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile

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Identification
Molecular formula
C17H14N2O
CAS number
75330-75-5
IUPAC name
3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile
State
State

At room temperature, 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile is in a solid state. It is typically handled in its solid form in various applications in laboratory and industrial contexts.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
272.30g/mol
Molar mass
272.3030g/mol
Density
1.2900g/cm3
Appearence

This compound appears as a crystalline solid, typically off-white to pale yellow in color. Its crystalline nature allows it to form well-defined, visible crystal structures. The color can vary slightly depending on purity and specific crystalline form.

Comment on solubility

Solubility of 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile

The solubility of 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile can be quite intriguing. Understanding how this compound interacts with various solvents is essential for its applications in both research and industry. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar Solvents: Compounds like this one, which contain hydroxyl groups, tend to have better solubility in polar solvents due to their ability to form hydrogen bonds.
  • Solvent Specificity: It's typically more soluble in solvents such as water and alcohols compared to nonpolar solvents like hexane or toluene.
  • Temperature Dependency: The solubility often increases with temperature; thus, heating the solvent may enhance the dissolution process.
  • pH Influence: The presence of acidic or basic conditions can affect solubility. The ionization of the hydroxyl group under different pH levels may lead to varying solubility behavior.

As quoted from solubility studies, "The dissolution process is not merely a physical phenomenon but involves complex interactions at the molecular level." Therefore, further research is often recommended to determine specific solubility values and behaviors in various conditions and formulations.

In conclusion, while some general trends can be defined, the solubility of 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile is multifaceted and deserves careful investigation under various conditions to fully understand its behavior in solution.

Interesting facts

Interesting Facts about 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile

3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile is a fascinating compound that showcases the remarkable versatility and complexity of organic molecules. Here are some intriguing insights about this compound:

  • Structural Unique Features: The compound features an indole core, which is a critical structure found in many natural products and pharmaceuticals. This highlights the importance of indole in medicinal chemistry.
  • Pharmacological Potential: Compounds with similar structures often exhibit various biological activities, including anticancer, antiviral, and antibacterial properties. Research is ongoing to explore the therapeutic potential of this compound.
  • Functional Groups: The presence of functional groups such as hydroxyl and cyano groups allows for interesting reactivity patterns and can influence the compound’s interactions in biological systems.
  • Application in Research: Scientists are keen on studying such compounds to develop novel drugs, particularly due to their ability to modulate biological pathways, which can be significant in treating diseases.
  • Interdisciplinary Interest: This compound bridges various fields, including organic synthesis, medicinal chemistry, and pharmacology, thus attracting attention from chemists and biologists alike.

As you delve deeper into the properties and potential applications of 3-(1-hydroxy-2-phenyl-ethyl)-1H-indole-5-carbonitrile, you might find yourself captivated by its contributions to science. Every compound opens a door to new possibilities and discoveries!

Synonyms
1-((5-Cyano)-3-indolyl)-2-phenyl ethanol
17380-27-7
1-Ethanol, 1-(5-cyano-3-indolyl)-2-phenyl-
3-(alpha-Hydroxyphenethyl)indole-5-carbonitrile
INDOLE-5-CARBONITRILE, 3-(alpha-HYDROXYPHENETHYL)-
3-(1-hydroxy-2-phenylethyl)-1H-indole-5-carbonitrile
DTXSID20938432