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Ivermectin

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Identification
Molecular formula
C48H74O14
CAS number
70288-86-7
IUPAC name
3-[[1-(isopentylcarbamoyl)-3-methyl-butyl]carbamoyl]oxirane-2-carboxylic acid
State
State

Ivermectin is in a solid state at room temperature. It is not soluble in water but can be dissolved in organic solvents such as methanol and ethanol.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
875.11g/mol
Molar mass
875.1060g/mol
Density
1.2150g/cm3
Appearence

At room temperature, Ivermectin typically appears as a white to yellowish powder. It is generally crystalline in nature with no discernible odor.

Comment on solubility

Solubility of 3-[[1-(isopentylcarbamoyl)-3-methyl-butyl]carbamoyl]oxirane-2-carboxylic acid

This compound, with the chemical formula C48H74O14, exhibits unique solubility characteristics due to its complex molecular structure. Understanding its solubility profile is crucial for various applications, particularly in pharmaceuticals and material science.

Factors Affecting Solubility

The solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of multiple functional groups in its structure can lead to varying polarities, affecting interactions with solvents.
  • Temperature: Increased temperature often enhances solubility, so studying the compound at different temperatures can provide valuable insights.
  • pH Level: The acidic nature of the compound suggests that its solubility may vary with changes in pH, especially in aqueous environments.
  • Nature of Solvent: Organic solvents may be more effective in dissolving this compound compared to water, due to its large hydrophobic components.

Predicted Solubility

While specific solubility data might be limited, it is generally expected that:

  • The compound may show moderate solubility in polar organic solvents.
  • It could exhibit low solubility in water, attributable to its substantial hydrophobic regions.

Understanding these solubility dynamics is essential for optimizing formulations and maximizing the effectiveness of this compound in practical applications. As always, empirical testing is recommended to establish precise solubility parameters in various conditions.

Interesting facts

Interesting Facts about 3-[[1-(Isopentylcarbamoyl)-3-methyl-butyl]carbamoyl]oxirane-2-carboxylic acid

This compound, a fascinating derivative of oxirane, holds significant interest due to its complex structure and potential applications in medicinal chemistry. Here are several noteworthy points about this compound:

  • Unique Structure: The presence of multiple functional groups (including the isopentyl carbamoyl and oxirane units) makes this compound particularly interesting for chemical synthesis. These features may influence its reactivity and interaction with biological systems.
  • Potential Pharmaceutical Applications: Compounds like this one can serve as leads in drug discovery. Due to the structural elements that may enhance bioactivity, they could potentially modulate biological pathways, contributing to therapeutic developments.
  • Oxirane Importance: The oxirane ring is a significant motif in organic chemistry, often used in the synthesis of various bioactive molecules. This compound exemplifies the functional versatility of epoxides in organic transformations.
  • Carbamoyl Group: The carbamoyl moiety introduces polar character to the molecule, which could influence its solubility properties, pharmacokinetics, and biological activity.

As a chemistry student, exploring compounds like this provides an opportunity to understand the intricate balance of structure and function in chemistry. Each modification in the molecular framework can lead to profound effects on the compound's behavior and interactions.

In conclusion, 3-[[1-(isopentylcarbamoyl)-3-methyl-butyl]carbamoyl]oxirane-2-carboxylic acid stands as an exciting compound for future research, potentially leading to breakthroughs in therapeutic applications. As we continue to study and modify such compounds, the possibilities within the realm of organic chemistry expand tremendously.

Synonyms
Loxistatin acid
L-trans-Epoxysuccinyl-Leu-3-methylbutylamide
3-[[4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
E-64-c
E-64c;EP 475
Loxistatin Acid (E-64C)
SCHEMBL1121089
HMS3653M20
IEC-4320-V
NCGC00018306-02
NCGC00018306-03
NCGC00163698-01
AS-78835
SW220063-1
BRD-A44872635-001-01-8
(L-3-trans-Carboxyoxirane-2-Carbonyl)-L-Leucine (3-Methylbutyl)Amide
3-({3-methyl-1-[(3-methylbutyl)carbamoyl]butyl}carbamoyl)oxirane-2-carboxylic acid