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3-(1-methylpyrrol-2-yl)pyridine

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Identification
Molecular formula
C10H10N2
CAS number
77437-40-2
IUPAC name
3-(1-methylpyrrol-2-yl)pyridine
State
State

At room temperature, 3-(1-methylpyrrol-2-yl)pyridine is found in a liquid state, which makes it useful for various chemical applications and reactions, particularly in organic synthesis.

Melting point (Celsius)
41.00
Melting point (Kelvin)
314.15
Boiling point (Celsius)
277.00
Boiling point (Kelvin)
550.15
General information
Molecular weight
158.20g/mol
Molar mass
158.2160g/mol
Density
1.0478g/cm3
Appearence

This compound is typically a clear to pale yellow liquid at room temperature. It has a characteristic slightly amine-like odor, common to many nitrogen-containing heterocycles.

Comment on solubility

Solubility of 3-(1-methylpyrrol-2-yl)pyridine

The solubility of 3-(1-methylpyrrol-2-yl)pyridine, a compound of interest in various chemical applications, can be influenced by several factors. Here are some key points regarding its solubility:

  • Polarity: The presence of nitrogen atoms in both the pyridine and the 1-methylpyrrol groups contributes to the overall polarity of the molecule. This polarity can enhance solubility in polar solvents.
  • Solvent Interaction: 3-(1-methylpyrrol-2-yl)pyridine typically exhibits good solubility in polar protic solvents such as water and alcohols, while its solubility in non-polar solvents may be limited due to less favorable interactions.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature. Hence, dissolving the compound in warm solvents can enhance its solubility.
  • Hydrogen Bonding: The compound's ability to participate in hydrogen bonding may facilitate its solubility in certain environments, making it more soluble in contexts where interactions with solvent molecules are possible.

In summary, the solubility of 3-(1-methylpyrrol-2-yl)pyridine is noteworthy due to its polarity and interactions with diverse solvents, allowing for a range of applications in various fields of chemistry. As stated, “like dissolves like,” making an understanding of the surrounding solvent crucial for predicting its behavior.

Interesting facts

Interesting Facts about 3-(1-methylpyrrol-2-yl)pyridine

3-(1-methylpyrrol-2-yl)pyridine is a fascinating compound with several noteworthy properties and applications:

  • Unique Structure: This compound features a distinctive arrangement of a pyridine ring fused with a 1-methylpyrrol moiety, which grants it unique chemical reactivity and allows it to interact with diverse biological targets.
  • Biological Applications: Compounds similar to 3-(1-methylpyrrol-2-yl)pyridine have been studied for their roles in medicinal chemistry. The properties of pyridine and its derivatives make them promising candidates for the development of new pharmaceuticals, particularly in targeting neurological diseases.
  • Ligands in Coordination Chemistry: Due to its ability to coordinate with metal ions, this compound can be utilized as a ligand in coordination chemistry, aiding in the synthesis of various metal complexes that exhibit interesting catalytic properties.
  • Electrochemical Properties: The electronic structure of the compound suggests that it may possess interesting electrochemical behavior, making it a candidate for applications in sensors and energy-related devices.
  • Research Perspective: The structural features of 3-(1-methylpyrrol-2-yl)pyridine provide a rich platform for chemists to study the relationship between molecular structure and biological activity. Many scientists are exploring its potential in drug design and development.

In conclusion, 3-(1-methylpyrrol-2-yl)pyridine is not just a simple compound; it brings a wealth of potential for research and application in the fields of medicinal chemistry, coordination chemistry, and materials science. Understanding its properties can lead to significant advancements in various scientific domains.

Synonyms
Nicotyrine
beta-Nicotyrine
XN4R1LH79Y
NSC-127943
NSC-407276
NICOTINE IMPURITY B (EP IMPURITY)
NICOTINE IMPURITY B [EP IMPURITY]
NICOTINE RESINATE IMPURITY B (EP IMPURITY)
NICOTINE RESINATE IMPURITY B [EP IMPURITY]
NICOTINE DITARTRATE DIHYDRATE IMPURITY B (EP IMPURITY)
NICOTINE DITARTRATE DIHYDRATE IMPURITY B [EP IMPURITY]
207-651-1
487-19-4
B-NICOTYRINE
3-(1-Methylpyrrol-2-yl)pyridine
3-(1-Methyl-1H-pyrrol-2-yl)pyridine
3,2'-Nicotyrine
3-(1-Methyl-2-pyrrolyl)pyridine
1-Methyl-2-(3-pyridyl)pyrrole
Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)-
.beta.-Nicotyrine
NSC 127943
ss-Nicotyrine
NSC 407276
CHEBI:7564
PYRIDINE, 3-(1-METHYL-2-PYRROLYL)-
NSC407276
Pyridine, 3-(1-methylpyrrol-2-yl)-
(3-(1-methyl-1h-pyrrol-2-yl)pyridine
|A-Nicotyrine
3-(1-Methyl-1H-pyrrol-2-yl)pyridine (beta-Nicotyrine)
UNII-XN4R1LH79Y
Nycotrine
-Nicotyrine
beta -Nicotyrine
MFCD00468104
SCHEMBL2996756
CHEMBL1522291
DTXSID3075048
1-methyl-2-(3-pyridyl) pyrrole
1-Methyl-4-(3-pyridinyl)pyrrole
BDBM109750
GLXC-02876
NSC127943
US8609708, 19 ?-Nicotyrine
US8609708, 19 beta-Nicotyrine
AKOS006280935
3-(1-methyl-1H-pyrrol-2-yl)-pyridine
NCGC00163362-01
3-(1-methyl-1H-pyrrole-2-yl)-pyridine
FN138662
TS-08096
NS00031819
EN300-309080
F78093
Q1987338
Z1198153878