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Nicotine N'-oxide

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Identification
Molecular formula
C10H14N2O
CAS number
97253-75-1
IUPAC name
3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium
State
State

At room temperature, nicotine N'-oxide can be found as a solid or a viscous liquid, depending on its form.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
259.00
Boiling point (Kelvin)
532.15
General information
Molecular weight
178.22g/mol
Molar mass
178.2240g/mol
Density
1.2800g/cm3
Appearence

Nicotine N'-oxide is typically a colorless or pale yellow liquid or crystalline solid. It may appear clear and viscous depending on its physical state.

Comment on solubility

Solubility of 3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium

The solubility of 3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium can be influenced by several factors, considering its unique structure. This compound has notable polar characteristics due to the presence of both a pyridinium ion and a nitrogen-containing heterocylic ring, which may enhance its interactions with polar solvents.

  • Water Solubility: Compounds with similar structures tend to exhibit good solubility in polar solvents like water. This is likely due to hydrogen bonding and ionic interactions.
  • Solvent Polarity: The solubility can further depend on the polarity of the solvent used. For example, it may be less soluble in non-polar solvents.
  • Temperature Dependence: Like many chemical compounds, solubility may increase with temperature, suggesting a greater degree of interaction under heated conditions.

As a chemical formulation, it is crucial to determine the solubility behavior in practical applications to ensure device compatibility and performance. Understanding the solubility profile of 3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium is key for its effective utilization in various chemical and pharmaceutical applications.

Interesting facts

Interesting Facts about 3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium

3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium is a compound that belongs to a class of molecules known for their unique structural and chemical properties. Here are some intriguing aspects to consider:

  • Biological Relevance: Compounds like this one often feature in medicinal chemistry, where their structural motifs can have significant interactions with biological targets.
  • Quaternary Ammonium Compound: The presence of a pyridinium ion signals that this compound carries a positive charge, making it highly soluble in polar solvents, allowing for diverse applications.
  • Structural Versatility: The combination of a pyridine and a pyrrolidine moiety creates opportunities for chiral synthesis, which is essential in the development of optically active pharmaceuticals.
  • Intermolecular Interactions: The oxido group enhances the ability of the molecule to engage in hydrogen bonding, which can lead to interesting self-assembly properties and stability in various environments.
  • Research Applications: This compound has potential uses in fields such as catalysis and materials science due to the ability to modify its properties through functionalization.

In summary, 3-(1-methylpyrrolidin-2-yl)-1-oxido-pyridin-1-ium embodies a fascinating intersection of organic chemistry, biology, and material sciences, with implications in drug design and synthetic methodologies.

Synonyms
rac-Nicotine 1-Oxide
23113-16-8
3-(1-methylpyrrolidin-2-yl)-1-oxidopyridin-1-ium
3-(1-methylpyrrolidin-2-yl)pyridine 1-oxide
(2'S)-Nicotine-1-oxide
nicotine oxide
starbld0022617
3-(1-Methyl-2-pyrrolidinyl)pyridine 1-oxide
SCHEMBL1538469
DB-228275