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3-(1-piperidylmethyl)-1H-indol-5-amine

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Identification
Molecular formula
C14H19N3
CAS number
107659-89-4
IUPAC name
3-(1-piperidylmethyl)-1H-indol-5-amine
State
State

The compound is in a solid state at room temperature.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.20
Boiling point (Celsius)
442.80
Boiling point (Kelvin)
716.00
General information
Molecular weight
241.32g/mol
Molar mass
241.3220g/mol
Density
1.1700g/cm3
Appearence

The compound is typically a crystalline powder at room temperature. It may appear as white to off-white crystals.

Comment on solubility

Solubility of 3-(1-piperidylmethyl)-1H-indol-5-amine

The compound 3-(1-piperidylmethyl)-1H-indol-5-amine exhibits unique solubility characteristics that are essential for its application in various chemical and pharmaceutical contexts. Understanding the solubility of this compound allows researchers to predict its behavior in biological systems and during synthesis.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Polarity: The presence of polar functional groups in the compound contributes to its solubility in polar solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can significantly enhance solubility, especially in protic solvents.
  • Temperature: As with many compounds, solubility can increase with rising temperature, which can lead to higher dissolution rates.

Solubility Profile

Though specific solubility data for 3-(1-piperidylmethyl)-1H-indol-5-amine may not be readily available, one can infer the following:

  • We can expect it to have moderate to high solubility in dimethyl sulfoxide (DMSO) and other organic solvents.
  • It may exhibit lower solubility in non-polar solvents like hexane or cyclohexane.
  • In aqueous solutions, the solubility may be pH-dependent, further influencing its bioavailability.

In conclusion, the solubility of 3-(1-piperidylmethyl)-1H-indol-5-amine plays a vital role in its functionality and utility. For researchers and practitioners, understanding how this compound behaves in various solvents can aid in optimizing its application in different environments.

Interesting facts

Interesting Facts about 3-(1-piperidylmethyl)-1H-indol-5-amine

The compound 3-(1-piperidylmethyl)-1H-indol-5-amine presents fascinating characteristics that intrigue both researchers and students alike. This organic compound belongs to the indole family, which is renowned for its diverse range of biological activities and applications.

Unique Structural Features

What sets 3-(1-piperidylmethyl)-1H-indol-5-amine apart are its structural intricacies:

  • Indole Core: The indole rings are often found in various natural products, making this compound a potential candidate for pharmaceutical development.
  • Piperidine Substituent: The presence of the piperidine group enhances its ability to interact with biological receptors, suggesting possible CNS activity.

Potential Applications

This compound has garnered attention for its potential applications in several fields:

  • Pharmacology: Research indicates that derivatives of this compound might be used in developing new medications for treating mental health disorders.
  • Probe Development: Given its structural properties, it could serve as a molecular probe for studying neurotransmitter systems.

Research Insights

Studies have indicated that compounds resembling 3-(1-piperidylmethyl)-1H-indol-5-amine:

  • Exhibit antidepressant-like effects
  • Possess anti-inflammatory properties

Quotes from various studies highlight its potential:

"The indole framework provides a rich scaffold for the development of novel therapeutic agents." - Journal of Medicinal Chemistry

Conclusion

With its intriguing structure and promising medicinal properties, 3-(1-piperidylmethyl)-1H-indol-5-amine stands as a compelling subject for ongoing research and exploration in the realm of medicinal chemistry. As scientists continue to uncover its potential, the future may hold exciting possibilities for this compound.

Synonyms
3414-76-4
INDOLE, 5-AMINO-3-(PIPERIDINOMETHYL)-
5-Amino-3-piperidinomethylindole
BRN 0404235
3-(Piperidinomethyl)-5-indoleamine
DTXSID50187739
DTXCID60110230
5-22-11-00288 (beilstein handbook reference)
3-(1-Piperidinylmethyl)-1H-indol-5-amine