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3-Piperidinopropionitrile

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Identification
Molecular formula
C8H14N2
CAS number
29943-42-8
IUPAC name
3-(1-piperidyl)propanenitrile
State
State

At room temperature, 3-Piperidinopropionitrile is in the liquid state.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
103.00
Boiling point (Kelvin)
376.15
General information
Molecular weight
124.21g/mol
Molar mass
124.1910g/mol
Density
0.9168g/cm3
Appearence

3-Piperidinopropionitrile is a colorless liquid.

Comment on solubility

Solubility of 3-(1-piperidyl)propanenitrile

3-(1-piperidyl)propanenitrile, a compound featuring a nitrile functional group linked to a piperidine ring, exhibits interesting solubility characteristics. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the nitrile group (-C≡N) contributes to the polarity of the molecule, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The piperidyl portion can engage in hydrogen bonding with solvents such as water, potentially increasing solubility in those environments.
  • Solvent Compatibility: Commonly, polar aprotic solvents such as DMSO (dimethyl sulfoxide) or DMF (dimethylformamide) are favored due to their ability to dissolve a wide range of organic compounds including nitriles.

However, it is also important to note that:

  • The solubility of 3-(1-piperidyl)propanenitrile might be limited in non-polar solvents due to its polar character.
  • When considering its application in various chemical reactions, the solubility can significantly impact reaction rates and product formation.

In summary, while 3-(1-piperidyl)propanenitrile tends to show good solubility in polar solvents, its effectiveness can vary depending on the solvent used. Understanding these nuances can be crucial for maximizing the compound's utility in both research and practical applications.

Interesting facts

Interesting Facts about 3-(1-Piperidyl)propanenitrile

3-(1-Piperidyl)propanenitrile is a fascinating compound that plays a significant role in both industrial applications and medicinal research. Here are some compelling points about this intriguing molecule:

  • Structural Significance: This compound contains a piperidine ring, which is a six-membered ring with one nitrogen atom. Piperidines are well-known building blocks in organic chemistry and are often found in various pharmaceuticals.
  • Versatile Applications: Its unique structure allows it to interact with a variety of biological targets, making it essential in the development of drugs, particularly in the field of neuroscience.
  • Research Potential: Studies have indicated that derivatives of 3-(1-piperidyl)propanenitrile may have anti-inflammatory and analgesic properties, highlighting its potential in pain management therapies.
  • Chiral Center: The presence of stereogenic centers lends the compound chirality, which can lead to different biological activities of its enantiomers. This is particularly important in pharmacology, where the activity of drugs can vary significantly between different isomers.
  • Real-World Impacts: Beyond its pharmaceutical implications, this compound also finds use in the synthesis of agrochemicals, showcasing the wide-ranging impact of organic compounds on various industries.

In essence, 3-(1-Piperidyl)propanenitrile is a prime example of how a single chemical structure can open doors to multiple fields of research and application, illustrating the interconnectedness of chemistry with medicine and industry.

Synonyms
3088-41-3
1-Piperidinepropanenitrile
1-PIPERIDINEPROPIONITRILE
3-Piperidinopropionitrile
beta-Piperidinopropionitrile
3-(1-Piperidine)propionitrile
BRN 0107858
EINECS 221-417-6
AI3-33248
DTXSID5062843
5-20-03-00047 (Beilstein Handbook Reference)
DTXCID8038277
221-417-6
3-piperidin-1-ylpropanenitrile
3-(piperidin-1-yl)propanenitrile
1-(2-Cyanoethyl)piperidine
3-(1-piperidino)propionitrile
3-(piperidin-1-yl)propionitrile
3-(N-Piperidino)propionitrile
MFCD00006511
1-Piperidine propionitrile
6B5B8RPT7L
SCHEMBL64284
.beta.-Piperidinopropionitrile
3-(1-Piperidinyl)propionitrile
CHEMBL1193996
3-(1-Piperidinyl)propanenitrile #
ALBB-004597
STK397830
AKOS000178246
AS-5631
DB-047928
CS-0216224
NS00028987
EN300-36713
Z53115952
InChI=1/C8H14N2/c9-5-4-8-10-6-2-1-3-7-10/h1-4,6-8H