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3-(1-piperidyl)propyl 4-fluoro-3-iodobenzoate

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Identification
Molecular formula
C15H19FNO2
CAS number
138057-31-8
IUPAC name
3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate
State
State

At room temperature, 3-(1-piperidyl)propyl 4-fluoro-3-iodobenzoate is primarily found in a solid state. It is stable under normal conditions but should be stored properly to avoid any moisture absorption that might affect its state and reactivity.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.00
Boiling point (Celsius)
428.50
Boiling point (Kelvin)
701.70
General information
Molecular weight
419.26g/mol
Molar mass
419.2610g/mol
Density
1.5200g/cm3
Appearence

This compound typically appears as an off-white to pale yellow solid. The exact shade can vary slightly depending on the purity and specific form (crystalline, powder, etc.). It may have a slight odor depending on the presence of impurities or decomposition products.

Comment on solubility

Solubility of 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate

The solubility of 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate exhibits some interesting characteristics that can influence its application in various settings.

Key Points on Solubility:

  • Polarity: This compound possesses polar functional groups due to the presence of the fluoro and iodo atoms, which often leads to increased solubility in polar solvents.
  • Solvent Compatibility: Typically, it is more soluble in solvents like methanol and ethanol compared to non-polar solvents like hexane.
  • Temperature Effects: Like many organic compounds, solubility can vary with temperature; increased temperatures may enhance the solubility of 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate.
  • Interactions: The interaction between the piperidyl group and various solvents plays a crucial role in determining solubility.

In summary, while 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate might not be soluble in all solvents, its behavior in polar environments presents valuable traits for its potential usage. As stated, "polar compounds thrive in polar solutions," making further exploration necessary for optimal application in pharmaceutical formulations.

Interesting facts

Interesting Facts about 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate

3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate is a fascinating compound that showcases the intricate relationship between structure and function in organic chemistry. Here are some key points that highlight its significance:

  • Pharmaceutical Potential: This compound could potentially serve as an important intermediate in the synthesis of various pharmaceuticals, particularly those targeting central nervous system disorders.
  • Unique Substitution Effects: The presence of both fluorine and iodine atoms in the aromatic ring introduces unique electronic and steric effects that can influence the compound's reactivity and biological activity.
  • Piperidine Influence: The piperidine ring, a six-membered nitrogen-containing heterocycle, is well-known for its role in enhancing the solubility and bioavailability of drug candidates.
  • Structure-Activity Relationship (SAR): Compounds like this one are crucial for SAR studies, where alterations in the chemical structure can lead to varied biological effects, aiding in drug design.
  • Applications in Research: As a chemical probe, 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate might be used in understanding receptor binding or enzyme inhibition in biochemical assays.

In the realm of medicinal chemistry, it is intriguing to explore how modifications to different parts of the molecule can yield compounds with drastically different properties. As one prominent chemist once said, "The beauty of chemistry lies in the details of structure." This compound stands as a testament to that beauty, embodying the potential for innovation in drug development.


Overall, 3-(1-piperidyl)propyl 4-fluoro-3-iodo-benzoate is not just a compound of interest due to its chemical makeup, but also a stepping stone towards unlocking new therapeutic avenues and enhancing our understanding of chemical interactions in biological systems.