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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[10-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid
State
State

At room temperature, iodixanol is typically in a solid crystalline state, highly soluble in water, which makes it suitable for use in medical formulations as a contrast agent.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
1550.23g/mol
Molar mass
1 550.2300g/mol
Density
2.0080g/cm3
Appearence

Iodixanol is a white to off-white crystalline powder. It is commonly used as a radiopaque contrast agent in medical imaging.

Comment on solubility

Solubility of 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid

The solubility of this complex compound is intricately related to its molecular structure and the presence of various functional groups. The compound contains multiple iodo substituents and carboxylic acid groups, which typically enhance interactions with polar solvents. Here are some key points to consider:

  • Polar Functional Groups: The carboxylic acid group is highly polar and can form hydrogen bonds with water, potentially increasing solubility.
  • Iodine Atoms: The presence of iodine, while increasing lipophilicity, may also introduce challenges in solubility in non-polar solvents.
  • Overall Molecular Structure: The presence of bulky groups, such as the oxopyrrolidinyl moiety, may hinder solvation, impacting the extent of solubility.

Generally, one might expect this compound to display limited solubility in non-polar solvents due to its extensive molecular size and bulkiness, while potentially exhibiting better solubility in polar solvents such as water or alcohols due to the influence of its functional groups. However, experimental determination is essential to ascertain the precise solubility characteristics.

In conclusion, the solubility of this compound is a balance between polar and non-polar interactions, making it an interesting subject for further studies in solubility behaviors.

Interesting facts

Interesting Facts about 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid

This compound is a fascinating example of a complex organic molecule with significant potential in the field of medicinal chemistry. Here are some key points that highlight its importance and uniqueness:

  • Structural Complexity: The compound features a multi-functional structure that includes various active groups, making it a subject of interest for drug development.
  • Triiodinated Design: The presence of triiodinated units enhances its utility as a contrast agent in medical imaging, particularly in X-rays and CT scans.
  • Biological Activity: The incorporation of a pyrrolidinyl moiety suggests potential biological activity, indicating that this compound could interact with various biological systems.
  • Applications in Cancer Research: Due to its complex configuration and the presence of iodine, this compound may play a role in targeting cancer cells for more effective imaging or therapy options.

Science often expresses the beauty of complexity, and this compound is no exception. As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This principle holds true as compounds like this pave the way for innovative pharmaceutical options through their intricate designs and functionalities.

In conclusion, investigating compounds like 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(2-oxopyrrolidin-1-yl)methyl]benzoic acid can unlock new frontiers in both chemistry and medicine, providing endless opportunities for development and exploration.

Synonyms
Benzoic acid, 3,3'-(sebacoyldiimino)bis(5-((2-oxo-1-pyrrolidinyl)methyl)-2,4,6-triiodo-
26090-51-7
BRN 1523595
3,3'-(Sebacoyldiimino)bis(5-((2-oxo-1-pyrrolidinyl)methyl)-2,4,6-triiodobenzoic acid)
DTXSID30180723