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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
State
State

Iodixanol is typically in a solid-state at room temperature.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
1550.15g/mol
Molar mass
1 550.1500g/mol
Density
1.6200g/cm3
Appearence

Iodixanol is a white or almost white, amorphous solid. In its pure form, it tends to appear as a crystalline powder. It is generally soluble in water.

Comment on solubility

Solubility of 3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid

The solubility of this complex compound can be quite intriguing due to its unique structural features and the presence of multiple functional groups. The solubility behavior can be summarized as follows:

  • Solvent Dependency: The compound’s solubility may vary significantly depending on the solvent used. Generally, compounds containing carboxylic acid groups, such as this one, tend to have increased solubility in polar solvents like water and ethanol.
  • pH Influence: The presence of the carboxylic acid group indicates that solubility could be affected by the pH of the solution. At higher pH levels, the carboxylic acid can deprotonate, which may enhance solubility in aqueous environments.
  • Hydrophobic Regions: The triiodo and methylcarbamoyl substitutions introduce hydrophobic characteristics. This may hinder solubility in non-polar solvents but could be beneficial for solubility in mixed or co-solvent systems.
  • Complex Formation: The potential for forming intermolecular interactions (such as hydrogen bonding) can also affect solubility. This compound may engage in such interactions, altering its solubility profile in comparison to simpler compounds.

In conclusion, while 3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid presents a framework rarely seen in conventional solubility discussions, its behavior is likely to be dictated largely by the interactions of its functional groups with the solvent. Further experimental investigations would be necessary to fully understand and quantify its solubility characteristics.

Interesting facts

Interesting Facts about 3-[[10-[3-Carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic Acid

This compound is a fascinating example of a highly functionalized organic molecule that demonstrates the intricate relationships between chemical structure and biological activity. Known for its complex architecture, it includes elements like multiple iodine atoms, which are noteworthy for several reasons:

  • Biochemical Applications: The presence of iodine, especially in the triiodinated positions, can significantly enhance the biological activity of the compound, making it a candidate for applications in medicinal chemistry.
  • Modulator of Biological Processes: The carboxylic acid and amide functionalities present in this structure might play crucial roles in modulating biological processes, which could be critical in pharmaceutical designs.
  • Therapeutic Potential: Compounds featuring both benzoic acid and carbamate moieties often exhibit intriguing pharmaceutical properties, including anti-inflammatory and antibacterial effects.
  • Study of Iodine Chemistry: Iodine's role in organic compounds is a topic of significant research interest, especially due to its implications in the synthesis of radiopharmaceuticals used in imaging and diagnosis.

From a synthetic perspective, the complexity of 3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid opens exciting pathways for chemical synthesis and modification. Chemists are often intrigued by such multi-functional compounds because:

  1. They can be used to probe various chemical reactions.
  2. They serve as templates for designing new drugs.
  3. They can highlight the interplay between structure and reactivity.

In summary, this compound represents a convergence of synthetics, pharmaceuticals, and biochemistry, embodying the intricacies and potential of modern organic chemistry. As interest in diverse organic compounds continues to grow, so does the significance of such structured entities in both research and application.

Synonyms
Iosefamic acid
losefamic acid
5591-33-3
Acido iosefamico
Acide iosefamique
MP-271
DRT553A48W
5,5'-(Sebacoyldiimino)bis(2,4,6-triiodo-N-methylisophthalamic acid)
Acidum josefamicum
Benzoic acid, 3,3'-((1,10-dioxo-1,10-decanediyl)diimino)bis(2,4,6-triiodo-5-((methylamino)carbonyl)-
Acidum iosefamicum [INN-Latin]
Acidum iosefamicum
Iosefamic acid [USAN:INN]
Acide iosefamique [INN-French]
Acido iosefamico [INN-Spanish]
MP 271
BRN 2800546
UNII-DRT553A48W
5,5'-(Octamethylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodoisophthalamic acid)
SCHEMBL38639
Iosefamic acid (USAN/INN)
IOSEFAMIC ACID [INN]
3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxodecanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
IOSEFAMIC ACID [USAN]
CHEMBL2106390
DTXSID80204509
CHEBI:177861
Isophthalamic acid, 5,5'-(octamethylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodo-
NS00125181
D04588
Q27276568