Skip to main content

Iodixanol

ADVERTISEMENT
Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[10-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid
State
State
At room temperature, iodixanol typically exists as a solid when in pure form. However, as it is primarily used in clinical settings as a contrast agent, it is more commonly encountered as a solution when used in diagnostic imaging procedures.
Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
285.20
Boiling point (Kelvin)
558.35
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
1.6200g/cm3
Appearence
Iodixanol is a white to off-white powder or solid, though in its practical applications, it is commonly found as a clear, colorless to pale yellow solution. This is particularly relevant when used in medical imaging as a contrast agent, where it is dissolved in water for injectable forms.
Comment on solubility

Solubility of 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid

The solubility of 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid in various solvents plays a crucial role in its applications and behavior in different environments. Here are some key points regarding the solubility characteristics of this complex compound:

  • Polarity: The presence of multiple functional groups, including the carboxylic acid and amide moieties, suggests that this compound may exhibit significant polarity, potentially increasing its solubility in polar solvents like water.
  • Hydrophobic Interactions: Conversely, the triiodinated rings may impart hydrophobic properties, making the compound less soluble in non-polar solvents.
  • pH Dependence: The carboxylic acid's solubility can be affected by pH; at lower pH levels, it may remain protonated, impacting solubility.
  • Concentration Effects: At higher concentrations, solubility may also be influenced by self-association or aggregation in solution, leading to decreased effective solubility.

Overall, the solubility of this compound can be perceived as a balance between its polar and non-polar characteristics, and a deeper understanding of these interactions is essential for predicting its behavior in various chemical processes.

Interesting facts

Interesting Facts about 3-[[10-[3-carboxy-2,4,6-triiodo-5-[(propanoylamino)methyl]anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-[(propanoylamino)methyl]benzoic acid

This compound is a fascinating example of how complex organic molecules can be engineered for specific applications, particularly in the field of medicinal chemistry. Here are some notable points:

  • Structural Complexity: The molecule features a highly intricate structure, which includes multiple iodine atoms. The presence of these halogens often enhances biological activity and can improve the imaging properties of compounds in medical diagnostics.
  • Antitumor Potential: Compounds like this one are studied for their potential use in cancer therapies. The unique arrangement of amino and carboxylic functional groups allows for interactions with biological macromolecules, which is pivotal in targeting cancer cells.
  • Bioconjugation: The presence of propanoylamino groups suggests potential for bioconjugation. This characteristic makes the compound versatile for drug delivery systems, where it can be linked to various biological molecules to improve efficacy and specificity in therapy.
  • Imaging Applications: The tri-iodinated nature of the compound positions it favorably for applications in medical imaging. Iodine is commonly used as a contrast agent in imaging techniques, such as computed tomography (CT) scans.
  • Research Studies: Ongoing research focuses on understanding how structural modifications influence pharmacokinetics and pharmacodynamics. Scientists are keenly interested in how these changes translate to therapeutic outcomes.

As a result of these attributes, compounds like this one offer rich avenues for research and development, making them valuable objects of study for both scientists and students interested in the intersection of chemistry and medicine.

Synonyms
BRN 2800795
BENZOIC ACID, 3,3'-(SEBACOYLDIIMINO)BIS(5-(PROPIONAMIDOMETHYL)-2,4,6-TRIIODO-
25901-42-2
DTXSID30180561
3,3'-(Sebacoyldiimino)bis(5-(propionamidomethyl)-2,4,6-triiodobenc acid)
RefChem:326963
DTXCID70103052