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Iodixanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
3-[[10-[3-carboxy-2,4,6-triiodo-5-(propylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(propylcarbamoyl)benzoic acid
State
State

At room temperature, Iodixanol is typically supplied as an aqueous solution, which makes it a liquid state preparation for use in various medical imaging procedures.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
872.00
Boiling point (Kelvin)
1 145.15
General information
Molecular weight
1550.20g/mol
Molar mass
1 550.1980g/mol
Density
2.0827g/cm3
Appearence

Iodixanol appears as a white, crystalline powder. In its commercial form, it is often supplied as a clear, colorless to pale yellow aqueous solution.

Comment on solubility

Solubility of 3-[[10-[3-carboxy-2,4,6-triiodo-5-(propylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(propylcarbamoyl)benzoic acid

The solubility of the compound with the chemical formula C35H44I6N6O15 presents several interesting factors to consider:

  • Polarity: Due to the presence of multiple functional groups, including carboxylic acid (-COOH) and amide (-CONH2) moieties, as well as a significant number of iodine atoms, the compound exhibits varied polarity traits.
  • Hydrophilicity vs. Hydrophobicity: While the carboxylic acid group contributes to hydrophilicity, the large triiodo and propylcarbamoyl groups increase hydrophobic characteristics. This duality can lead to complex solubility behavior.
  • Solubility in Solvents: The compound is anticipated to be more soluble in organic solvents like dimethyl sulfoxide (DMSO) or ethanol compared to water, owing to its hydrophobic regions. However, certain formulations or modifications might enhance its aqueous solubility.
  • Temperature Dependency: The solubility may also be affected by temperature changes, with increased temperatures likely enhancing solvation, especially in organic solvents.

As a whole, the solubility profile of this compound is complex and highly dependent on external factors, which calls for careful experimental assessment in relevant media to determine practical applications. In summary, while it is expected to be relatively soluble in specific organic solvents, its overall solubility behavior warrants a thorough investigation to unlock its full potential.

Interesting facts

Interesting Facts about 3-[[10-[3-carboxy-2,4,6-triiodo-5-(propylcarbamoyl)anilino]-10-oxo-decanoyl]amino]-2,4,6-triiodo-5-(propylcarbamoyl)benzoic Acid

This compound is a remarkable example of how complex organic molecules can be designed for specific functions, particularly in the field of medicinal chemistry. With its intricate structure housing multiple functional groups and iodine atoms, it exemplifies the integration of pharmacology and biochemistry.

Key Features:

  • Iodine-rich structure: The presence of triiodo groups in the molecular structure suggests that this compound may have interesting properties in imaging applications, such as in radiology or as a contrast agent.
  • Carboxylic acid functionality: The carboxylic acid groups in the compound indicate potential for reactivity and interactions with various biological targets, making it worth studying for therapeutic purposes.
  • Amide linkages: The inclusion of propylcarbamoyl groups may enhance the compound's lipophilicity, aiding in cellular permeability, a crucial factor for drug design.

In the context of scientific research, it is particularly intriguing how such compounds are synthesized and their significance in the study of disease mechanisms. As Dr. Roger Adams once said, "The greatest discoveries are made by complex structures that have simple beginnings." This compound encapsulates that philosophy, paving the way for innovative applications and exciting research opportunities.

Applications:

  • Pharmaceutical research: With its potential bioactivity, this compound may be explored against various disease targets.
  • Diagnostic imaging: Its iodine content makes it an ideal candidate for exploration in imaging techniques.
  • Chemical probes: The unique structure could serve as a chemical probe for studying biological processes or mechanism-based research.

Overall, the study of such a complex compound opens doors to understanding not only chemical interactions but also the broader implications on human health and disease.

Synonyms
10395-30-9
BRN 2800691
Isophthalamic acid, 5,5'-(octamethylenebis(carbonylimino))bis(N-propyl-2,4,6-triiodo-
DTXSID20146156
5,5'-(Octamethylenebis(carbonylimino))bis(N-propyl-2,4,6-triiodoisophthalamic acid)
DTXCID1068647
3-[[10-[3-carboxy-2,4,6-triiodo-5-(propylcarbamoyl)anilino]-10-oxodecanoyl]amino]-2,4,6-triiodo-5-(propylcarbamoyl)benzoic acid