Zotepine | Solubility of Things

Identification

Molecular formula

C₁₈H₁₈ClNS

CAS number

26615-21-4

IUPAC name

3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine

State

At room temperature, zotepine is typically found in a solid state as a crystalline powder. This form is stable under standard conditions of temperature and pressure.

Melting point (Celsius)

202.00

Melting point (Kelvin)

475.15

Boiling point (Celsius)

470.15

Boiling point (Kelvin)

743.15

General information

Molecular weight

327.87g/mol

Molar mass

327.8660g/mol

Density

1.2200g/cm³

Appearence

Zotepine typically appears as a light yellow to practically white crystalline powder. This can vary slightly based on the purity and specific form of the sample. It is not very soluble in water, which is consistent with many compounds used in pharmaceutical applications.

Comment on solubility

Solubility of 3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine

The solubility of 3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine is an intriguing aspect of its chemical behavior. Here are some key points to consider:

Polarity: Due to its complex structure that includes both aromatic and aliphatic components, the compound may exhibit varying degrees of polarity, which can significantly influence its solubility in different solvents.
Solvent Interaction: This compound is likely to be more soluble in organic solvents such as dichloromethane or ethanol due to the presence of non-polar aromatic rings. The solubility in water might be limited.
Temperature Effects: As with many compounds, solubility can be temperature-dependent. Generally, an increase in temperature often enhances solubility, particularly in organic solvents.
Functional Groups: The presence of the amine group suggests potential for hydrogen bonding with polar solvents, which could increase solubility in certain conditions.

In conclusion, understanding the solubility of 3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine requires a careful examination of its molecular structure and the nature of its interactions with various solvents. While its solubility may not be straightforward, identifying these facets can provide valuable insights into its application and behavior in chemical environments.

Interesting facts

Interesting Facts about 3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine

This compound, with a complex molecular structure, has garnered attention in various fields, particularly in medicinal chemistry and pharmacology. Here are some engaging insights into its significance:

Targeting Disorders: Compounds like this one are often studied for their potential therapeutic roles in treating a range of psychiatric disorders. Their unique structure can interact with neurotransmitter systems in profound ways.
Chlorine Substitution: The presence of chlorine in the structure can enhance the compound's efficacy by increasing lipophilicity and influencing metabolic stability, which are crucial for its pharmacological activity.
Role of Benzothiepin: The benzothiepin core is of particular interest due to its association with various biological activities, including neuroprotective effects. Such structural motifs can be pivotal in drug design.
Dimethylation: The dimethylamino group in this compound can contribute to its hydrophilicity and ionization properties, which are important for the compound's absorption and excretion in biological systems.
Research Potential: There is ongoing research into the synthesis and modulation of such compounds to enhance their therapeutic profiles, showcasing the dynamism of medicinal chemistry.

In conclusion, 3-(10-chloro-6H-benzo[c][1]benzothiepin-11-ylidene)-N,N-dimethyl-propan-1-amine represents a fascinating intersection of organic chemistry and pharmacology, with potential implications that extend to the development of novel therapeutic agents. As scientists continue to explore its properties and effects, this compound may unlock new avenues for treatment and understanding of complex mental health issues.