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Ibuprofen

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Identification
Molecular formula
C13H18O2
CAS number
15687-27-1
IUPAC name
3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid
State
State

Ibuprofen is a solid at room temperature.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.15
Boiling point (Celsius)
157.00
Boiling point (Kelvin)
430.15
General information
Molecular weight
206.28g/mol
Molar mass
206.2830g/mol
Density
1.0360g/cm3
Appearence

Ibuprofen appears as a white crystalline powder.

Comment on solubility

Solubility of 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid

The solubility of 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid in various solvents is influenced by its unique chemical structure. This compound features both hydrophobic and hydrophilic regions which can affect its interaction with solvents. Here are some important points to consider regarding its solubility:

  • Hydrolysis: The hydroxy (-OH) group increases the potential for hydrogen bonding, enhancing solubility in polar solvents like water.
  • Hydrophobic interactions: The dimethylpropyl group contributes to hydrophobicity, which may limit solubility in polar environments, making it more soluble in organic solvents such as ethanol and dichloromethane.
  • Solvent effects: This compound may demonstrate variable solubility depending on the polarity of the solvent used; for example, it may be more soluble in aqueous alcohol solutions compared to pure water.

Overall, while 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid may possess some degree of solubility in water, its complete solubility profile is best explored in a range of both polar and non-polar solvents to fully understand its behavior in different chemical environments.

Interesting facts

Interesting Facts About 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid

3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid, commonly referred to in organic chemistry as a *substituted benzoic acid*, exhibits fascinating characteristics that make it a compound of interest to scientists and students alike.

Key Features

  • Functional Groups: This compound features both a hydroxyl group and a carboxylic acid group, which contribute to its potential as a versatile building block in organic synthesis.
  • Chirality: The presence of the dimethylpropyl group introduces stereogenic centers, allowing for interesting stereoisomeric forms. This aspect is crucial when considering the compound's biological activity.
  • Biological Relevance: Compounds of this nature can often exhibit interesting *pharmacological properties*, making them potential candidates for further research in medicinal chemistry.

Applications

The versatility of 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid extends beyond theoretical interest:

  • It may serve as a precursor in the synthesis of more complex pharmaceuticals.
  • The unique structural features can influence its interactions in biological systems, providing insight into drug design and development.

Research Insights

In the realm of research, understanding the structure-activity relationship (SAR) of such compounds is critical:

  • Evaluating how the substitutions on the benzene ring affect its activity can lead to the discovery of more effective agents in treating various conditions.
  • By investigating different derivatives, scientists can optimize the properties of the compound, enhancing its therapeutic potential.

In conclusion, 3-(1,2-dimethylpropyl)-2-hydroxy-6-methyl-benzoic acid stands as a compelling candidate for various applications in organic and medicinal chemistry, raising questions and challenges that spark the curiosity of chemists around the world.

Synonyms
2-Methyl-5-(2-(3-methylbutyl))salicylic acid
20717-17-3
BRN 2840233
3-(1,2-Dimethylpropyl)-2,6-cresotic acid
2,6-CRESOTIC ACID, 3-(1,2-DIMETHYLPROPYL)-
2-hydroxy-6-methyl-3-(3-methylbutan-2-yl)benzoic acid
DTXSID50942926