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3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole

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Identification
Molecular formula
C14H18N2
CAS number
3556-92-3
IUPAC name
3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole
State
State
At room temperature, 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole is a solid.
Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
212.31g/mol
Molar mass
212.2880g/mol
Density
1.2000g/cm3
Appearence
3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole typically appears as a crystalline solid. Its color may range from white to off-white, depending on purity and the presence of any impurities.
Comment on solubility

Solubility of 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole

The solubility of 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole is influenced by several factors, making its behavior in various solvents quite fascinating to study. Here are some key aspects to consider:

  • Polarity: This compound has a relatively complex structure and is moderately polar. Depending on the solvent, it can dissolve effectively in polar solvents like water and ethanol.
  • Hydrogen Bonding: The presence of nitrogen atoms may allow for hydrogen bonding, enhancing solubility in solvents that can also form hydrogen bonds.
  • Solvent Compatibility: Traditional organic solvents such as DMSO or methanol may provide better solubility than non-polar solvents, due to the polar nature of the compound.
  • pH Effects: Changes in pH can significantly affect solubility, especially if the compound can ionize. For instance, at high pH, the solubility in water may increase.

In summary, the solubility of 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole can be optimized using the right choice of solvent and conditions. Understanding the underlying principles of solubility will be crucial for its application in various chemical processes and pharmaceuticals.

Interesting facts

Exploring 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole

The compound 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole presents an intriguing blend of structural features that can capture the attention of both researchers and students. Here are some noteworthy aspects of this unique compound:

  • Structural Complexity: The presence of both an indole moiety and a pyrrolidine ring offers a compelling fusion of functionality. Indoles are widely recognized for their significant role in biological systems, being a fundamental structure in various natural products and pharmaceuticals.
  • Biological Interest: Indole derivatives are known to exhibit a range of pharmacological activities. For example, they can act as neurotransmitter modulators, which may be beneficial in the development of treatments for disorders such as depression and anxiety.
  • Synthesis Potential: The synthesis of this compound might involve various organic reactions, showcasing synthetic techniques such as alkylation or cyclization. This provides rich ground for practical laboratory exploration and reinforces theoretical concepts encountered in organic chemistry coursework.
  • Research Applications: The study of such compounds is vital in medicinal chemistry. Their derivatives can often lead to discoveries in drug development, highlighting the importance of structure-activity relationships for understanding the biological effects of chemical entities.
  • Interdisciplinary Connections: This compound serves as an excellent example of where chemistry intersects with biology and pharmacology, making it relevant for a multidisciplinary approach in scientific studies.

In conclusion, 3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole is more than just a compound; it is a gateway to understanding complex biochemical interactions and synthetic methodologies. As one delves deeper into its structure and potential, the excitement of discovery in the realm of chemistry is palpable!

Synonyms
3-(1,4-dimethylpyrrolidin-2-yl)-1H-indole
802578-98-9
3-(1,4-Dimethyl-2-pyrrolidinyl)-1H-indole
DB-276829
INDOLE, 3-(1,4-DIMETHYL-2-PYRROLIDINYL)-