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Nicotine tert-indole

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Identification
Molecular formula
C16H20N2
CAS number
1535490-20-4
IUPAC name
3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole
State
State

At room temperature, the compound is typically in a solid state.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
240.34g/mol
Molar mass
240.3390g/mol
Density
1.2000g/cm3
Appearence

The compound is usually in a solid crystalline form. It appears as off-white or light brown colored powder.

Comment on solubility

Solubility of 3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole

3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole, a complex organic compound, exhibits unique solubility characteristics that are pivotal for its application in various fields. Understanding its solubility can facilitate better utilization in chemical reactions and formulations.

  • Polar vs. Non-Polar Solvents: This compound is likely to have a higher solubility in polar solvents due to the presence of nitrogen atoms in the pyrrolidine and indole structures.
  • Log P Value: The partition coefficient (Log P) can provide insight into its hydrophilicity or hydrophobicity, influencing solubility in environmental and biological systems.
  • Temperature Dependency: Solubility may increase with temperature, which is common for many organic compounds; hence, warm solvent conditions can enhance dissolution.

In summary, "Solubility depends on structure, solvent type, and environmental factors." The solubility profile of 3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole indicates it may perform effectively in varied chemical environments, making it an interesting candidate for further study and practical applications.

Interesting facts

Interesting Facts about 3-(1,5-Dimethylpyrrolidin-2-yl)-1H-Indole

3-(1,5-Dimethylpyrrolidin-2-yl)-1H-indole is a fascinating compound that draws attention for its unique structure and potential applications. As a derivative of indole, a fundamental building block in organic chemistry, this compound exhibits intriguing characteristics and pharmacological properties.

1. Structural Significance

The presence of the 1,5-dimethylpyrrolidin moiety adds a layer of complexity to the indole structure, enabling diverse interactions with biological targets. Specifically, its structure can influence:

  • Receptor binding: The unique arrangement may enhance its ability to interact with various receptors in the body.
  • Chemical reactivity: Alterations in its electronic distribution can affect its reactivity and stability under different conditions.

2. Biological Potential

This compound is notable for its potential therapeutic applications. Research has indicated that indole derivatives can possess:

  • Antidepressant effects: Some studies suggest that compounds similar to 3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole may exhibit mood-enhancing properties.
  • Anticancer activity: Indole derivatives are known for their ability to interfere with cancer cell proliferation.
  • Antimicrobial properties: There is growing interest in the antimicrobial effects of indole-based compounds, making this a subject of intense study.

3. Applications in Synthesis

Beyond its biological significance, 3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole serves as an important precursor in organic synthesis, utilized in creating other complex molecules. It can be used in:

  • Pharmaceutical research: As a scaffold for drug design, facilitating the development of new therapeutics.
  • Material science: In the synthesis of polymers and novel materials due to its unique chemical properties.

In summary, 3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole exemplifies how **structural innovation** in chemical compounds can lead to significant advancements in both scientific research and real-world applications. Its potential as a multi-functional compound enhances its value in both academic and industrial settings.

Synonyms
3-(1,5-dimethylpyrrolidin-2-yl)-1H-indole
19137-66-7
3-(1,5-Dimethyl-2-pyrrolidinyl)-1H-indole
BRN 0612755
3-(1,5-Dimethyl-2-pyrrolidinyl)indole
INDOLE, 3-(1,5-DIMETHYL-2-PYRROLIDINYL)-
DTXSID10940741