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Indole-3-pyruvic acid

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Identification
Molecular formula
C11H9NO3
CAS number
771-51-7
IUPAC name
3-(1H-indol-3-yl)-2-oxo-propanoic acid
State
State

At room temperature, Indole-3-pyruvic acid is a solid.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.00
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.00
General information
Molecular weight
189.19g/mol
Molar mass
189.1770g/mol
Density
1.3830g/cm3
Appearence

Indole-3-pyruvic acid is generally found as a crystalline powder.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)-2-oxo-propanoic acid

The solubility of 3-(1H-indol-3-yl)-2-oxo-propanoic acid (C11H9NO3) is a fascinating aspect that reflects its interactions with solvents and influences its behavior in chemical processes. Understanding the solubility characteristics can aid in various applications, including pharmaceuticals and organic synthesis.

Key points regarding its solubility include:

  • Polar vs Nonpolar Solvents: This compound is likely to exhibit greater solubility in polar solvents, such as water and alcohols, due to its functional groups that can engage in hydrogen bonding.
  • pH Dependence: The solubility may vary significantly with changes in pH, as the carboxylic acid group can donate protons, thus influencing the ionic form.
  • Temperature Effects: Increased temperature generally enhances solubility; therefore, the compound might dissolve more readily at elevated temperatures.

In summary, the solubility of C11H9NO3 is moderated by its molecular structure and environmental conditions, making it essential to consider these factors when working with this compound in any chemical context. The versatility of solubility is what makes this compound intriguing in both research and practical applications.

Interesting facts

Interesting Facts about 3-(1H-indol-3-yl)-2-oxo-propanoic acid

3-(1H-indol-3-yl)-2-oxo-propanoic acid, also known by its intriguing alternative name, is a compound that bridges the gap between organic chemistry and biomedical research. Here are several fascinating aspects of this compound:

  • Biological Significance: This compound exhibits important biological activities, particularly in the context of its role as an intermediate in the synthesis of various biologically active molecules. Its indole structure is commonly found in many natural products and pharmacologically active compounds.
  • Potential Therapeutic Uses: Researchers are continuously investigating the therapeutic potential of compounds like 3-(1H-indol-3-yl)-2-oxo-propanoic acid. It has shown promise in studies related to:
    • Cancer treatment due to its ability to inhibit certain cancer cell lines.
    • Neuroprotective effects, which may offer insights into treatments for neurodegenerative diseases.
  • Structure and Reactivity: The unique structure of this compound allows it to participate in various chemical reactions, making it a versatile building block in organic synthesis.
  • Research Versatility: The compound is a subject of interest in multidisciplinary fields, including medicinal chemistry, pharmacology, and material science, showcasing its versatility.
  • Indole Chemistry: As a member of the indole family, this compound highlights the captivating chemistry of indoles, which are known for their unique aromatic properties and varied reactivity patterns.

In summary, 3-(1H-indol-3-yl)-2-oxo-propanoic acid is more than just a chemical formula; it represents a promising area of study with significant implications for health and disease management. As we continue to explore the depths of its properties and uses, the compound remains a beacon of hope in advancing scientific discovery.

Synonyms
Indole-3-pyruvic acid
392-12-1
3-(1H-Indol-3-yl)-2-oxopropanoic acid
Indole-3-pyruvate
3-Indolylpyruvic acid
indolepyruvate
Indolyl-3-pyruvate
Indolepyruvic acid
3-(indol-3-yl)pyruvic acid
indol-3-yl pyruvic acid
3-Indolylpyroracemic acid
3-Indolepyruvic acid
beta-Indolepyruvic acid
beta-Indolylpyruvic acid
3-(3-Indolyl)-2-oxopropanoic acid
Indole-3-pyruvic acid monohydrate
NSC 88874
1H-Indole-3-propanoic acid, alpha-oxo-
EINECS 206-874-1
alpha-Oxo-1H-indole-3-propanoic acid
BRN 0172966
4QM0LT13A8
DTXSID3042053
KETO TRYPTOPHAN
(Indol-3-yl)pyruvate
NSC-88874
(indol-3-yl)pyruvic acid
1H-Indole-3-propanoic acid, .alpha.-oxo-
DTXCID1022053
CHEBI:29750
5-22-06-00324 (Beilstein Handbook Reference)
1H-INDOLE-3-PROPANOIC ACID, .ALPHA.-OXO
3IO
Indole pyruvic acid
UNII-4QM0LT13A8
3-indol-3-yl-2-oxopropanoic acid
3-Indolpyruvic acid
MFCD00005640
indol-3-pyruvic acid
3-indole-pyruvic acid
.beta.-Indolepyruvic acid
.beta.-Indolylpyruvic acid
bmse000646
bmse000685
1H-Indole-3-pyruvic acid
MLS000515792
SCHEMBL125249
CHEMBL485012
HMS2270A21
NSC88874
Tox21_301365
STL286879
AKOS005267243
FI30479
HY-W028393
NCGC00247042-01
NCGC00255790-01
AC-10208
AS-63461
CAS-392-12-1
SMR000112266
3-(1H-indol-3-yl)-2-keto-propionic acid
Indole-3-pyruvic acid, >=98.0% (TLC)
CS-0072417
NS00014851
1H-INDOLE-3-PROPANOIC ACID, ALPHA-OXO
1H-Indole-3-propanoic acid, alpha-oxo-(9CI)
C00331
EN300-218335
3-(1H-indol-3-yl)-2-oxidanylidene-propanoic acid
AC17FD8D-94BC-4C87-B5E6-D2B60F03B45D
BRD-K09109825-001-07-3
Q23905803
F9995-2651