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Indole-3-acrylic acid

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Identification
Molecular formula
C11H9NO2
CAS number
826-03-9
IUPAC name
3-(1H-indol-3-yl)prop-2-enoic acid
State
State
Indole-3-acrylic acid is typically in a solid state at room temperature and pressure, appearing as crystalline powder.
Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
185.19g/mol
Molar mass
185.1910g/mol
Density
1.3200g/cm3
Appearence

Indole-3-acrylic acid appears as a beige to light brown crystalline powder. It has a distinctive odor typical of aromatic compounds.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)prop-2-enoic acid

The solubility of 3-(1H-indol-3-yl)prop-2-enoic acid, also known as indole-3-propionic acid, presents an interesting case in the study of organic compounds. The solubility of this compound can be influenced by various factors:

  • Solvent Polarity: Like many organic acids, the solubility in polar solvents such as water is typically higher compared to non-polar solvents. This is due to the ability of polar solvent molecules to stabilize ionic forms of the acid.
  • Temperature Effects: Increased temperature often enhances solubility. As temperature rises, the kinetic energy of molecules increases, leading to better interaction between solute and solvent.
  • pH Considerations: As a carboxylic acid, 3-(1H-indol-3-yl)prop-2-enoic acid can dissociate in aqueous solutions. The degree of ionization can vary with pH, impacting its solubility.

In general, while 3-(1H-indol-3-yl)prop-2-enoic acid demonstrates a certain degree of solubility in water, it is important to highlight that its solubility is moderate and can be considered favorable in organic solvents. Understanding these solubility characteristics is crucial for applications in pharmaceuticals and biochemical research.

Interesting facts

Exploring 3-(1H-indol-3-yl)prop-2-enoic acid

3-(1H-indol-3-yl)prop-2-enoic acid is a fascinating compound that showcases the intriguing relationship between organic chemistry, biology, and medicinal applications. Here are some captivating aspects of this compound:

  • Structure and Function: The presence of the indole moiety contributes to its biological activity, making it a compound of interest in both pharmaceutical and agricultural chemistry.
  • Biological Significance: Compounds derived from indole are often noted for their antimicrobial, anticancer, and anti-inflammatory properties, suggesting that 3-(1H-indol-3-yl)prop-2-enoic acid may share some of these beneficial effects, although its specific activities may need further exploration.
  • Applications in Research: Due to its structural characteristics, this compound can serve as a valuable building block in organic synthesis, potentially leading to the development of new drugs or agricultural agents.
  • Link to Natural Products: This compound resembles metabolites found in various natural products, hinting at its potential role in plant defense mechanisms or interactions within biological systems.

As scientists continue to unravel the complexities of bioactive compounds, 3-(1H-indol-3-yl)prop-2-enoic acid exemplifies the potential to bridge gaps between chemistry and real-world applications, emphasizing the importance of interdisciplinary approaches in scientific research.

Synonyms
2-Propenoic acid, 3-(1H-indol-3-yl)-
3-(1H-indol-3-yl)prop-2-enoic acid
indol-3-acrylic acid
3-Indoleacrylic acid D4
SCHEMBL179873
ARD2385D4
AKOS028108383
SY008927
DB-041551
(2Z)-3-(1H-indol-3-yl)prop-2-enoic acid