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Tryptamine

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Identification
Molecular formula
C10H12N2
CAS number
61-54-1
IUPAC name
3-(1H-indol-3-yl)propan-1-amine
State
State

At room temperature, tryptamine is a solid. It is generally stable under standard conditions and should be stored in a cool, dry place to maintain its integrity.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
378.40
Boiling point (Kelvin)
651.55
General information
Molecular weight
160.22g/mol
Molar mass
160.2220g/mol
Density
1.1880g/cm3
Appearence

Tryptamine typically appears as a white to off-white crystalline solid. Its form can vary based on the specific derivative and the conditions under which it is stored or synthesized.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)propan-1-amine

The solubility of 3-(1H-indol-3-yl)propan-1-amine in various solvents is an important aspect to consider for its potential applications in pharmaceuticals and chemical research.

Solubility Characteristics

  • Aqueous Solubility: 3-(1H-indol-3-yl)propan-1-amine displays limited solubility in water, which is common for many indole derivatives due to their hydrophobic nature. However, modest solubility may occur at higher temperatures or in alkaline conditions.
  • Organic Solvents: It is generally more soluble in organic solvents such as ethanol, methanol, and DMSO. This solubility trend is typical for amines that possess aromatic structures.
  • pH Dependence: The solubility of this compound may vary with pH levels, as amines can exist in protonated forms that are more soluble in aqueous environments.

In summary, the solubility of 3-(1H-indol-3-yl)propan-1-amine illustrates the influence of chemical structure on solubility behavior, revealing key insights for its synthesis and potential applications. Understanding these solubility properties allows researchers to optimize conditions for its use in different chemical environments.

Interesting facts

Interesting Facts About 3-(1H-indol-3-yl)propan-1-amine

3-(1H-indol-3-yl)propan-1-amine, also known as tryptamine, is a fascinating compound that is noteworthy for its role in both biology and medicinal chemistry. Here are some interesting aspects to consider:

  • Biochemical Precursor: Tryptamine serves as a biosynthetic precursor to several important neurotransmitters, including serotonin, which plays a crucial role in mood regulation, sleep, and digestion.
  • Natural Occurrence: This compound is widely found in nature, particularly in plants, fungi, and even in the tissues of animals, showcasing its integral role in various biochemical pathways.
  • Alkaloid Features: Tryptamine is classified as an alkaloid, a group of naturally occurring organic compounds that are mostly basic and often have significant pharmacological effects.
  • Receptor Interaction: The compound has shown affinity for several serotonin receptors, which is why it's studied in the context of psychological and neurological conditions, including depression and anxiety disorders.
  • Research and Therapeutics: Emerging studies suggest the potential therapeutic uses of tryptamine and its derivatives in treating mental health disorders, thus marking its significance in contemporary pharmaceutical research.

As chemists continue to explore the diverse functionalities of 3-(1H-indol-3-yl)propan-1-amine, its contributions to both natural sciences and therapeutic applications make it a compound of great interest. Whether you are studying biology, pharmacology, or organic chemistry, understanding the properties and implications of this compound is essential!

Synonyms
6245-89-2
1H-Indole-3-propylamine
1H-Indole-3-propanamine
EINECS 228-361-1
DTXSID00211492
DTXCID00133983
228-361-1
(1H-Indol-3-yl)-1-propanamine
3-(1H-indol-3-yl)propan-1-amine
MFCD00130194
Homotryptamine
3-(Indol-3-yl)propanamine
(1H-lndol-3-yl)-1-propanamine
3-indol-3-ylpropylamine
3-(3-aminopropyl)indole
Oprea1_526363
SCHEMBL735189
SCHEMBL5000681
3-(1H-indol-3-yl)propylamine
CHEMBL2229708
SCHEMBL28421998
SCHEMBL29532652
3-(1H-indol-3-yl)-propylamine
BBL020229
SBB088945
STK386772
AKOS001476511
CS-W018622
FS-2717
FS-3765
3-(1H-Indol-3-yl)-1-propanamine #
[3-(1H-indol-3-yl)-prop-1-yl]amine
NCGC00342755-01
SY042804
DB-073122
NS00035035
EN300-72181
AB01334180-02
A1-04140
F1160-0010
Z275361382