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Indole-3-propylamine hydrochloride

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Identification
Molecular formula
C11H15ClN2
CAS number
15534-15-9
IUPAC name
3-(1H-indol-3-yl)propylammonium;chloride
State
State

At room temperature, Indole-3-propylamine hydrochloride is in a solid state. It is typically stored as a stable crystalline powder which is both air and moisture sensitive, and should therefore be kept in a dry, cool place.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
326.00
Boiling point (Kelvin)
599.00
General information
Molecular weight
200.70g/mol
Molar mass
200.7000g/mol
Density
1.1550g/cm3
Appearence

Indole-3-propylamine hydrochloride is a white to off-white crystalline powder. It is typically available in a fine powdered form, showing high solubility in water, which gives it a potential characteristic sheen under certain lighting conditions.

Comment on solubility

Solubility of 3-(1H-indol-3-yl)propylammonium chloride

The solubility of 3-(1H-indol-3-yl)propylammonium chloride (C12H15ClN2) is influenced by its ionic nature and the presence of functional groups in its structure. As a quaternary ammonium salt, it is expected to exhibit high solubility in polar solvents, particularly in water. This property is primarily due to:

  • Ion-Dipole Interactions: The charged ammonium ion readily interacts with water molecules, enhancing its solubility.
  • Hydrogen Bonding: The indole moiety may contribute to solubility by forming hydrogen bonds with solvent molecules.
  • Effect of Chloride Ion: The chloride ion, being a small and highly solvated ion, also aids in overall solubility when dissolved in polar solvents.

In contrast, the compound may display limited solubility in non-polar solvents due to the lack of favorable interactions. As a general guideline:

  1. **Highly soluble** in water and other polar solvents.
  2. **Slightly soluble** or **insoluble** in non-polar solvents.

In conclusion, 3-(1H-indol-3-yl)propylammonium chloride is predominantly soluble in aqueous environments, making it an essential compound for various biochemical applications where solubility is crucial for effective interaction and transport within physiological systems.

Interesting facts

Interesting Facts about 3-(1H-indol-3-yl)propylammonium Chloride

3-(1H-indol-3-yl)propylammonium chloride is a fascinating compound known for its association with significant biological and chemical activities. Here are some intriguing points about this compound:

  • Biological Importance: The indole structure in this compound is known for its presence in many biologically active molecules, including neurotransmitters like serotonin and hormones.
  • Pharmacological Potential: Compounds containing indole groups are studied for their potential therapeutic effects in areas such as oncology, psychiatry, and neurology, making this compound of interest in medicinal chemistry.
  • Signaling Molecule: Due to its structure, 3-(1H-indol-3-yl)propylammonium chloride can function as a signaling molecule, possibly affecting various receptor pathways and cellular mechanisms.
  • Ammonium Ion Interaction: The ammonium moiety adds to its potential for ion exchange properties, which could be leveraged in various applications in materials science and drug delivery.
  • Synthesis and Applications: The synthesis routes for this compound often involve straightforward organic reactions, making it accessible for research purposes.

As a future researcher or student in the field of chemistry, understanding compounds like 3-(1H-indol-3-yl)propylammonium chloride opens doors to exploring complex biochemical interactions and innovative therapeutic developments. This compound is just one example of how simple structures can lead to profound impacts in science.

Synonyms
Indole-3-propylamine hydrochloride
NSC 76866
gamma-3-Indolylpropylamine hydrochloride
3-(gamma-Aminopropyl)-indole hydrochloride
INDOLE, 3-(3-AMINOPROPYL)-, MONOHYDROCHLORIDE