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Digoxin

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Identification
Molecular formula
C41H64O14
CAS number
20830-75-5
IUPAC name
3-[(1R,3S,5S,10R,11R,13R,14S,17R)-1,3,5,11,14-pentahydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
State
State

Digoxin is typically found in a solid state at room temperature. It is administered as an oral tablet or via injection.

Melting point (Celsius)
249.00
Melting point (Kelvin)
522.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
780.95g/mol
Molar mass
780.9470g/mol
Density
1.2800g/cm3
Appearence

Digoxin is a white, odorless, and crystalline powder. It is typically administered in its pure form or as part of a pharmaceutical preparation.

Comment on solubility

Solubility of 3-[(1R,3S,5S,10R,11R,13R,14S,17R)-1,3,5,11,14-pentahydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

The solubility of complex compounds like 3-[(1R,3S,5S,10R,11R,13R,14S,17R)-1,3,5,11,14-pentahydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one can vary greatly based on several factors. Understanding its solubility characteristics is crucial for effective application, particularly in pharmaceutical formulations and biochemical processes. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl groups suggests a degree of polarity, which may enhance solubility in polar solvents such as water.
  • Hydrophobic Interactions: The dodecahydro structure may introduce hydrophobic characteristics, potentially reducing solubility in aqueous environments.
  • Temperature Influence: Solubility can be affected by temperature changes; warming the solvent may increase the solubility of the compound.
  • pH Levels: The solubility might also be influenced by the pH of the solvent; for compounds with functional groups that can ionize, solubility can greatly increase in more acidic or basic conditions.

In summary, the solubility of this compound is influenced by its structural complexity, with both polar and non-polar characteristics playing a role. It highlights the importance of conducting solubility tests in various solvents to ascertain the most effective formulation strategies.

Interesting facts

Interesting Facts about 3-[(1R,3S,5S,10R,11R,13R,14S,17R)-1,3,5,11,14-pentahydroxy-10-(hydroxymethyl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

This complex organic compound belongs to a class of molecules that are characterized by their intricate structures and diverse biological activities. Here are some intriguing aspects to consider:

  • Structural Complexity: The compound features multiple hydroxyl groups, which are key to its reactivity and interaction with biological systems. Such a structure often indicates potential for various applications in medicine and biochemistry.
  • Natural Occurrences: Compounds with furan-5-one moieties are often found in nature and can act as natural products, suggesting important roles in plant metabolism and ecological interactions.
  • Insect Hormones: Compounds structurally similar to this one are known to play roles in insect physiology, potentially acting as hormone mimics or inhibitors, with applications in pest management and agricultural biochemistry.
  • Potential Medicinal Uses: Given its intricate stereochemistry and functional groups, research into this compound could reveal significant pharmacological properties, including anti-inflammatory, antioxidant, or anticancer effects.

With research ongoing, this compound stands at the intersection of chemistry and biochemistry, offering countless opportunities for discovery. As with many natural compounds, the challenge lies in elucidating its mechanisms of action and finding effective applications. Scientists are encouraged to invest time in studying similarly complex molecules, as they may unlock new pathways in the treatment of diseases.

In the words of a seasoned chemist, "Complexity is the essence of life; understanding it is where the true magic begins."

Synonyms
SCHEMBL18924992