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3-[2-(1-Piperidyl)ethyl]-1H-indole

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Identification
Molecular formula
C15H20N2
CAS number
70572-69-3
IUPAC name
3-[2-(1-piperidyl)ethyl]-1H-indole
State
State

At room temperature, 3-[2-(1-Piperidyl)ethyl]-1H-indole is in a solid state. It must be handled with care as it can decompose under specific conditions, and standard precautions for handling solid organic compounds should be observed.

Melting point (Celsius)
106.10
Melting point (Kelvin)
379.30
Boiling point (Celsius)
490.70
Boiling point (Kelvin)
763.90
General information
Molecular weight
256.36g/mol
Molar mass
256.3580g/mol
Density
1.1550g/cm3
Appearence

3-[2-(1-Piperidyl)ethyl]-1H-indole is typically a crystalline solid. It is off-white to light brown in color and can appear as a powder when finely ground. The compound does not exhibit luminescence or opalescence under normal lighting conditions.

Comment on solubility

Solubility of 3-[2-(1-piperidyl)ethyl]-1H-indole

The solubility of 3-[2-(1-piperidyl)ethyl]-1H-indole can be described with several important considerations:

  • Polarity: This compound may exhibit moderate polarity due to the presence of the piperidyl group and the indole structure. Such characteristics often influence solubility in various solvents.
  • Solvent Interactions: It is likely more soluble in organic solvents such as methanol, ethanol, or dimethyl sulfoxide (DMSO), rather than in water, due to its hydrophobic indole core.
  • Practical Applications: Understanding the solubility can guide researchers in the preparation of solutions for biological assays and pharmacological studies, where ensuring proper solubility is crucial.

In conclusion, while the precise solubility parameters may require empirical determination, it is clear that the structural features of 3-[2-(1-piperidyl)ethyl]-1H-indole play a significant role in its solubility profile, potentially favoring organic solvents over aqueous environments.

Interesting facts

Exploring 3-[2-(1-piperidyl)ethyl]-1H-indole

3-[2-(1-piperidyl)ethyl]-1H-indole is a fascinating compound that belongs to the indole family, a class of compounds known for their diverse biological activities. The structure of this compound features an indole ring, which is a bicyclic compound consisting of a fused benzene and pyrrole ring. This unique architecture contributes to its significant role in various fields, particularly in medicinal chemistry.

Key Features of 3-[2-(1-piperidyl)ethyl]-1H-indole

  • Pharmacological Potential: This compound has garnered attention for its potential therapeutic effects. Studies suggest that indole derivatives may exhibit a range of biological activities including anti-inflammatory, anticancer, and neuroprotective properties.
  • Serotonin Receptor Interaction: Due to its indole backbone, this compound may interact with serotonin receptors, which could influence mood, cognition, and perception. Such interactions are of considerable interest in developing antidepressants and other psychiatric drugs.
  • Structural Variability: The presence of the piperidyl group in the compound enhances its ability to modulate receptor activity, making it a versatile scaffold for further structural modifications that can fine-tune its pharmacological properties.
  • Applications in Drug Design: The compound serves as a potential lead in drug discovery. The ability to modify the indole and piperidine moieties opens up numerous avenues for developing novel therapies for various diseases.

As researchers continue to unravel the complexities of compounds like 3-[2-(1-piperidyl)ethyl]-1H-indole, it becomes increasingly clear that these molecules hold great promise in the fields of chemistry and pharmacology. The ongoing exploration of their properties, mechanisms, and therapeutic potentials may lead to significant advancements in medical science.

Synonyms
26628-87-5
INDOLE, 3-(2-PIPERIDINOETHYL)-
DTXSID70181173
3-[2-(1-piperidinyl)ethyl]-1H-indole
3-(2-(1-Piperidinyl)ethyl)-1H-indole
RefChem:1066457
DTXCID80103664
3-(2-piperidin-1-ylethyl)-1H-indole
3-(2-(piperidin-1-yl)ethyl)-1h-indole
MLS003171325
3-[2-(piperidin-1-yl)ethyl]-1H-indole
3-(2-Piperidinoethyl)indole
NSC 374698
BRN 0178668
3-[2-(1-PIPERIDINYL)ETHYL]INDOLE
NSC374698
3-(2-piperidin-1-yl-ethyl)-1H-indole
SCHEMBL734226
CHEMBL2138465
AKOS015967426
NSC-374698
SMR001875226