Skip to main content

Bleomycin

ADVERTISEMENT
Identification
Molecular formula
C55H84N17O21S3
CAS number
11056-06-7
IUPAC name
3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxo-propyl]amino]-3-oxo-propyl]-5-methyl-pyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-4-carbonyl]amino]propyl-dimethyl-sulfonium
State
State
Bleomycin is generally handled as a solid lyophilized powder in its delivery form. At room temperature, once reconstituted with a diluent, it is handled in liquid form as a clear solution for injection.
Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1415.57g/mol
Molar mass
1 415.5670g/mol
Density
1.2000g/cm3
Appearence
Bleomycin is typically available as a powder for injection. It appears as a hygroscopic, white to pale yellow, amorphous powder. When reconstituted with a suitable solvent, it forms a clear solution.
Comment on solubility

Solubility of the Compound

The solubility of the compound 3-[[2-[2-[2-[[(2S,3R)-2-[[[2S,3S,4R)-4-[[(2S,3S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxo-propyl]amino]-3-oxo-propyl]-5-methyl-pyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-4-carbonyl]amino]propyl-dimethyl-sulfonium is a complex issue due to its intricate structure and multifunctional groups. It typically exhibits varying degrees of solubility depending on environmental conditions such as pH and temperature. Here are some key points regarding its solubility:

  • Hydrophilicity vs. Hydrophobicity: The presence of multiple polar functional groups suggests that the compound may have a degree of hydrophilicity, enhancing solubility in aqueous solutions.
  • Influence of Side Chains: The various amino and hydroxyl groups may interact with water molecules, potentially increasing solubility.
  • Salt Formation: If the compound can form salts with acids, its solubility in water may significantly improve.
  • Temperature Dependence: Solubility may increase at higher temperatures, which is a common characteristic of many organic compounds.

In conclusion, while this compound may exhibit some solubility in polar solvents due to its functional groups, exact solubility metrics would require experimental determination under specific conditions. As with many complex molecules, the interplay of structural features and environmental factors makes this an interesting subject for further study.

Interesting facts

Interesting Facts About 3-[[2-[2-[2-[[(2S,3R)-2-[[[2S,3S,4R)-4-[[(2S,3S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxo-propyl]amino]-3-oxo-propyl]-5-methyl-pyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-4-carbonyl]amino]propyl-dimethyl-sulfonium

This compound is a fascinating example of complex organic chemistry, showcasing a plethora of functional groups and structural intricacies. Here are some exciting points worth noting:

  • Structural Complexity: The compound's name hints at an elaborate structure, featuring multiple thiazole rings, amino groups, and diverse carbohydrate moieties, making it a structural marvel in the realm of chemical compounds.
  • Biological Significance: Compounds with similar configurations are often explored for their biological activities. They could serve as important leads in drug development, particularly in areas like antimicrobial and anticancer therapies.
  • Chirality: The compound includes several chiral centers, which can lead to different isomers that may exhibit varied biological effects. Chirality plays a critical role in pharmacology, influencing how drugs interact with biological systems.
  • Potential Applications: Given its complex structure, this compound could be utilized in various fields such as medicine, pharmacology, and biotechnology, potentially paving the way for innovative therapeutic agents.
  • Research Frontiers: The synthesis and study of such complex molecules provide insights into synthetic methodology, reaction mechanisms, and the strategic development of new materials.

In summary, the intricate design of this compound not only reflects the beauty of chemistry but also underscores the potential for significant contributions to scientific research and medicinal chemistry. As we advance our understanding of such compounds, we inch closer to solving some of the most pressing health challenges of our time.