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Triethylene glycol diamine

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Identification
Molecular formula
C9H22N2O3
CAS number
4246-51-9
IUPAC name
3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine
State
State

At room temperature, triethylene glycol diamine is a liquid. It is viscous and hygroscopic, making it necessary to handle it with care to prevent unwanted absorption of moisture.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
176.25g/mol
Molar mass
176.2450g/mol
Density
1.0665g/cm3
Appearence

Triethylene glycol diamine is a colorless to pale yellow liquid with a mild amine-like odor. It is hygroscopic, meaning it readily absorbs water from the air, which can affect its appearance if exposed for prolonged periods. The compound is clearly in liquid form under standard temperature conditions and is typically used as a curing agent in epoxy.

Comment on solubility

Solubility of 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine

The solubility of 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine in various solvents is an interesting aspect of its behavior. Due to its structure, several factors influence its solubility:

  • Polarity: This compound contains multiple ether groups, which can enhance its water solubility. The presence of hydrophilic amine groups may also contribute positively to its solubility in polar solvents.
  • Hydrogen Bonding: The amino groups can engage in hydrogen bonding with water molecules, potentially increasing solubility.
  • Chain Length: The length of the hydrocarbon chains may impact solubility. Typically, longer chains may reduce solubility in water but increase solubility in organic solvents.

Based on these factors, one could expect the compound to be more soluble in:

  • Polar Solvents: Like water and alcohols, where its polar functional groups can interact effectively.
  • Organic Solvents: Such as DMSO or DMF, where both polar and non-polar interactions can occur.

In summary, while specific experimental solubility data may be required for precise applications, the structural characteristics suggest that 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine demonstrates good solubility in polar solvents, particularly due to its ability to engage in hydrogen bonding and its polar functional groups.

Interesting facts

Interesting Facts about 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine

The compound 3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine is a fascinating member of the class of organic compounds known for their biological significance and potential therapeutic uses. Here are some interesting facts about this compound:

  • Structure & Function: This compound features a branched structure that can enhance its ability to interact with biological molecules, making it a subject of study in pharmacology.
  • Amine Group: The presence of amino groups in the structure often contributes to increased reactivity and the ability to form hydrogen bonds, which is essential for its functionality in biological systems.
  • Applications: Compounds with similar structures are often researched for their potential roles in drug delivery systems, particularly in targeting specific cells or tissues. This makes them promising candidates in the development of new pharmaceuticals.
  • Synthetic Routes: The synthesis of this compound may involve multiple steps, including nucleophilic substitutions and etherifications, showcasing the versatility of organic synthesis techniques.
  • Biochemical Implications: The compound could potentially mimic natural neurotransmitters or hormones, offering insight into designing new drugs aimed at neurological conditions.

As scientists continue to explore this compound, its unique properties may shed light on new therapeutic pathways and enhance our understanding of complex biochemical interactions.

In the words of chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound is a prime example of how one structure can lead to many innovative ideas in science and medicine.

Synonyms
4246-51-9
4,7,10-Trioxa-1,13-tridecanediamine
Diethylene Glycol Bis(3-aminopropyl) Ether
4,7,10-trioxatridecane-1,13-diamine
EINECS 224-207-2
Di(3-aminopropyl) ether of diethylene glycol
BRN 1760709
DIETHYLENE GLYCOL, DI(3-AMINOPROPYL) ETHER
3,3'-Oxybis(ethyleneoxy)bis(propylamine)
DPA-DEG
95W232H4RT
1-Propanamine, 3,3'-(oxybis(2,1-ethanediyloxy))bis-
1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-
Q 19262
ANCAMINE 1922
3,3'-(Oxybis(2,1-ethanediyloxy))bis-1-propanamine
3,3'-[Oxybis(2,1-ethanediyloxy)]bis-1-propanamine
O,O'-Bis(3-aminopropyl)diethylene glycol
EC 224-207-2
Bis[2-(3-aminopropoxy)ethyl] Ether
1,13-diamino-4,7,10-trioxatridecane
3,3'-[OXYBIS(ETHANE-2,1-DIYLOXY)]DIPROPAN-1-AMINE
BIS(2-(3-AMINOPROPOXY)ETHYL) ETHER
4,7,10-TRIOXA-1,13-TRIDECANAMINE
PROPYLAMINE, 3,3'-(OXYBIS(ETHYLENEOXY))BIS-
3,3'-(OXYBIS(ETHANE-2,1-DIYLOXY))DIPROPAN-1-AMINE
diethyleneglycol diaminopropyl ether
4,7,10Trioxa1,13tridecanediamine
O,O'Bis(3aminopropyl)diethylene glycol
Diethylene glycol bis(3aminopropyl)ether
3,3'Oxybis(ethyleneoxy)bis(propylamine)
Diethylene glycol, di(3aminopropyl) ether
Di(3aminopropyl) ether of diethylene glycol
3,3'(Oxybis(2,1ethanediyloxy))bis1propanamine
1Propanamine, 3,3'(oxybis(2,1ethanediyloxy))bis
1-Propylamine, 3,3'-(oxybis(ethyleneoxy))bis-(6CI,7CI,8CI)
1Propylamine, 3,3'(oxybis(ethyleneoxy))bis (6CI,7CI,8CI)
3,3'-((Oxybis(ethane-2,1-diyl))bis(oxy))bis(propan-1-amine)
Bis-NH2-C1-PEG3
PROTAC Linker 24
3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine
MFCD00059850
Propylamine-PEG3-Propylamine
DTXSID6044565
Trioxa-1,13-tridecanediamine,4,7,10-,
3-{2-[2-(3-aminopropoxy)ethoxy]ethoxy}-1-propanamine
3-{2-[2-(3-AMINOPROPOXY)ETHOXY]ETHOXY}PROPAN-1-AMINE
C10H24N2O3
UNII-95W232H4RT
SCHEMBL25842
CHEMBL3187499
DTXCID4024565
Tox21_301509
AKOS000348730
AT11312
NCGC00255812-01
4,7,10-trioxa-1,13-tridecane diamine
BP-23734
BS-17252
DA-60312
SY029951
CAS-4246-51-9
Diethylene glycol-bis(3-aminopropyl) ether
HY-128844
CS-0077127
D1571
4,7,10-Trioxa-1,13-tridecanediamine, 97%
EN300-383885
1-Propylamine, 3,3'-(oxybis(ethyleneoxy))bis-
Q27271827