Interesting facts
Interesting Facts about 3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-2-methyl-pyrido[1,2-a]pyrimidin-4-one
This compound, a member of the pyrimidine family, showcases the remarkable complexity that can arise in organic chemistry. Not only does it possess a unique structure, but it also offers intriguing possibilities for various applications:
- Pharmaceutical Potential: Compounds of this nature often serve as important intermediates in pharmaceutical development. Structurally diverse compounds with piperidine moieties are recognized for their role in enhancing the pharmacological profiles of drugs.
- Fluorine Substitution: The presence of fluorine in organic compounds can significantly alter their biological activity. Fluorine is known to improve metabolic stability and lipophilicity, making this compound potentially more effective as a therapeutic agent.
- Multi-Functional Groups: This molecule contains multiple functional groups that can be tailored for specific interactions. The various regions of the molecule may facilitate targeted interactions with biological receptors, enhancing its efficacy.
- Structure-Activity Relationship (SAR): Understanding the SAR of such a compound could lead to the development of new drugs that more effectively combat diseases. Chemists focus on how changes in structure influence activity, paving the way for optimized therapeutic agents.
As noted by renowned chemist Robert H. Grubbs, “The beauty of chemistry lies in the diversity of its compounds and the endless possibilities they offer for innovation.” This compound is a perfect example of that beauty in action. With its intricate design and the potential for impactful applications, it serves as an excellent subject for further exploration in drug discovery and synthetic research.
In summary, the complexity and potential of this compound make it an exciting topic for both students and professionals alike. Engaging with such compounds not only enhances one’s understanding of organic chemistry but also opens doors to advancements in various scientific fields.
Synonyms
Pirenperone
75444-65-4
Pirenperona
R-47,465
3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
R-47465
NSC-760095
CHEMBL18331
MLS000069365
Y9FMC4513X
DTXSID9045182
4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl-
4H-Pyrido[1,2-a]pyrimidin-4-one,3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-
NCGC00015784-07
SMR000058507
3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido-[1,2-a] pyrimidin-4-one
R 47465
DTXCID7025182
Pirenperonum
Pirenperonum [INN-Latin]
Pirenperona [INN-Spanish]
CAS-75444-65-4
SR-01000002998
EINECS 278-213-5
UNII-Y9FMC4513X
Pirenperone [USAN:INN:BAN]
3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-(2-(4-(4-FLUOROBENZOYL)PIPERIDIN-1-YL)ETHYL)-2-METHYL-4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE
3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; R 47465;
Prestwick_858
Spectrum_001584
SpecPlus_000663
Lopac-P-126
Opera_ID_1876
Prestwick0_000531
Prestwick1_000531
Prestwick2_000531
Prestwick3_000531
Spectrum2_001680
Spectrum3_001655
Spectrum4_000620
Spectrum5_001827
PIRENPERONE [INN]
Pirenperone (USAN/INN)
PIRENPERONE [USAN]
3-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
PIRENPERONE [MART.]
Pirenperone, >97%, solid
Lopac0_001007
BSPBio_000541
BSPBio_003409
GTPL283
KBioGR_001180
KBioSS_002064
MLS001148188
MLS001424212
DivK1c_006759
SCHEMBL467209
SPECTRUM1504188
SPBio_001899
SPBio_002462
BPBio1_000597
CHEBI:92444
KBio1_001703
KBio2_002064
KBio2_004632
KBio2_007200
KBio3_002629
GLXC-10116
HMS1569L03
HMS1922F15
HMS2051H22
HMS2093C08
HMS2096L03
HMS2234F07
HMS3263I15
HMS3370M02
HMS3393H22
HMS3713L03
Pharmakon1600-01504188
HY-B1737
Tox21_110220
Tox21_501007
BDBM50024205
CCG-39087
MFCD00069332
NSC760095
AKOS030530791
Tox21_110220_1
LP01007
NC00316
NSC 760095
SDCCGSBI-0050980.P004
3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[2,1-b]pyrimidin-4-one
NCGC00015784-01
NCGC00015784-02
NCGC00015784-03
NCGC00015784-04
NCGC00015784-05
NCGC00015784-06
NCGC00015784-08
NCGC00015784-09
NCGC00015784-10
NCGC00015784-11
NCGC00015784-12
NCGC00015784-14
NCGC00015784-19
NCGC00021326-03
NCGC00021326-04
NCGC00021326-05
NCGC00021326-06
NCGC00178084-01
NCGC00178084-02
NCGC00261692-01
FP172697
TS-08449
SBI-0050980.P003
DB-294027
CAS- 75444-65-4
CS-0013748
EU-0101007
NS00059920
P-126
S0779
VU0239628-6
D05495
G92074
AB00053292_16
EN300-23224971
L000956
SR-01000002998-2
SR-01000002998-5
SR-01000002998-7
BRD-K25224017-001-05-2
BRD-K25224017-001-15-1
BRD-K25224017-001-25-0
Q27088400
Z2169367190
3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one(Pirenperone)
3-{2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl}-2-methyl- 4H-pyrido[1,2-a]pyrimidine-4-one
Solubility of 3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-2-methyl-pyrido[1,2-a]pyrimidin-4-one
The compound 3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-2-methyl-pyrido[1,2-a]pyrimidin-4-one (C26H26FN3O) presents an intriguing case in terms of solubility. When evaluated for solubility in various solvents, the following observations may be noted:
Furthermore, solubility can be considerably influenced by temperature; increasing the temperature often enhances solubility for many organic compounds. Hence, it's essential to conduct solubility evaluations under various conditions to acquire comprehensive insights.
Overall, the solubility profile of this compound highlights its complexity, influenced by both structural attributes and the chemical environment. For optimal formulation strategies, understanding the solubility behavior could pave the way for improved application in pharmaceuticals.