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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine
State
State

Nitrofurazone is generally in a solid state at room temperature.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1550g/mol
Density
1.6700g/cm3
Appearence

Nitrofurazone typically appears as a yellow crystalline powder. It is commonly used in some medical and veterinary applications due to its antibacterial properties, often added in ointments and solutions.

Comment on solubility

Solubility of 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine

The solubility of 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine can be quite complex due to its unique chemical structure. Here are some important considerations regarding its solubility:

  • Polarity: The presence of a nitro group and the oxadiazole ring may contribute to varying polar characteristics, which can influence how it interacts with solvents.
  • Solvent Selection: This compound might exhibit better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol, compared to polar solvents like water.
  • Temperature Dependency: As is common with many organic compounds, an increase in temperature might enhance solubility, making the compound more soluble in hot solvents.
  • pH Influence: The solubility can also change with pH, especially if the compound can be ionized in acidic or basic conditions.

In essence, while specific solubility values might require experimental determination, understanding these factors can provide insight into how 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine behaves in various environments. It is important to note that adequate solubility is often essential for its application in chemical synthesis and biological studies.

Interesting facts

Interesting Facts about 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine

This compound, known as 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine, belongs to the class of oxadiazoles, which are five-membered aromatic heterocycles containing nitrogen. These compounds are particularly noteworthy due to their diverse applications in medicinal chemistry and materials science.

Key Features

  • Bioactivity: Oxadiazoles have been studied for their potential pharmacological properties, including antimicrobial, antifungal, and anticancer activities.
  • Structural Diversity: The incorporation of a nitro group and a vinyl moiety in this compound introduces unique electronic properties, enhancing its potential reactivity and application in organic synthesis.
  • Materials Science: Compounds like this one are often explored for their usefulness in the development of new materials, including organic semiconductors and dyes.
  • Research Potential: The structure presents opportunities for further investigation into the mechanisms of action in biological systems, leading to the development of new therapeutic agents.

As a promising candidate in the field of organic chemistry, 3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazol-5-amine exemplifies the ongoing quest for innovative compounds that can address various challenges in drug development and materials engineering.

In conclusion, the exploration of oxadiazol derivatives could potentially lead to significant advancements in various scientific fields. This compound highlights the intricate relationship between structure and function in chemical compounds, making it a fascinating subject of study for both researchers and students alike.

Synonyms
3-[2-(5-nitrofuran-2-yl)ethenyl]-1,2,4-oxadiazol-5-amine
21959-57-9
5-Amino-3-(2-(5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole
BRN 1079486
S 18506
SCHEMBL7854603
DTXSID40860423
1,2,4-Oxadiazole, 5-amino-3-(2-(5-nitro-2-furyl)vinyl)-
1,2,4-Oxadiazol-5-amine, 3-(2-(5-nitro-2-furanyl)ethenyl)-