Skip to main content

Fluticasone Propionate

ADVERTISEMENT
Identification
Molecular formula
C25H31F2O5S
CAS number
80474-14-2
IUPAC name
3-[2-(9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonic acid
State
State

Fluticasone Propionate is a solid at room temperature and is typically used in powder form for pharmaceutical applications.

Melting point (Celsius)
274.50
Melting point (Kelvin)
547.65
Boiling point (Celsius)
486.50
Boiling point (Kelvin)
759.65
General information
Molecular weight
500.55g/mol
Molar mass
500.5500g/mol
Density
1.4900g/cm3
Appearence

The compound appears as a white powder. It is usually free-flowing and non-crystalline in texture.

Comment on solubility

Solubility of 3-[2-(9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonic acid

The solubility of the compound 3-[2-(9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonic acid (C25H31F2O5S) can be intriguing given its complex chemical structure. Here are some key highlights regarding its solubility:

  • Polar Characteristics: The presence of sulfonic acid and hydroxyl groups suggests that the compound may exhibit increased solubility in polar solvents, particularly water.
  • Non-Polar Elements: The large hydrocarbon portion of the compound may lead to solubility challenges in non-polar solvents, indicating a potential preference for aqueous environments.
  • Acidic Properties: As a sulfonic acid, its functionality may allow for ionization in aqueous solutions, enhancing solubility under certain pH conditions.
  • Temperature Dependence: The solubility is likely to be temperature-dependent, with increased temperatures often leading to greater solubility in many compounds.

Overall, while the presence of functional groups indicates favorable solubility in certain solvents, the extensive structure also introduces complexities. The balance between hydrophilic and hydrophobic regions will dictate the solubility profile, making it essential to assess specific solvent conditions for optimal dissolution.

Interesting facts

Interesting Facts about 3-[2-(9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethoxy]carbonylbenzenesulfonic acid

This compound, a complex organic molecule, has garnered attention not only for its intricate structure but also for its potential applications in medicinal chemistry. Here are some fascinating points about this compound:

  • Structure Complexity: The molecule features a unique combination of steroid-like and aromatic systems that contribute to its biological activity.
  • Potential Pharmaceutical Applications: Due to its steroidal backbone, it has been studied for applications in treating various conditions, including hormonal disorders and certain types of cancer.
  • Fluorination Insight: The presence of a fluorine atom enhances the compound's metabolic stability, making it an interesting candidate for drug development. Fluorinated compounds often exhibit improved pharmacokinetic profiles.
  • Biological Activity: Similar compounds have shown promise as anti-inflammatory agents, highlighting the importance of understanding this compound's interactions within biological systems.
  • Research Significance: Researchers are keenly interested in derivatives of this compound, as modifying specific functional groups can lead to a range of therapeutic properties.

As scientists continue to explore the depths of its chemical behavior and biological interactions, knowing compounds like this one can pave the way for innovative solutions in the field of medicine.

Synonyms
DTXSID30859846
3-{[(9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl)oxy]carbonyl}benzene-1-sulfonic acid