Skip to main content

Metanephrine

ADVERTISEMENT
Identification
Molecular formula
C9H13NO3
CAS number
5001-33-2
IUPAC name
3-(2-amino-1-hydroxy-ethyl)phenol
State
State
At room temperature, metanephrine is typically found in a solid state. It is stable and can be stored at room temperature when properly sealed and away from moisture and light.
Melting point (Celsius)
219.00
Melting point (Kelvin)
492.00
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.00
General information
Molecular weight
183.20g/mol
Molar mass
183.2040g/mol
Density
1.2830g/cm3
Appearence

Metanephrine appears as a white to off-white crystalline solid. It can also appear as a white powder depending on the form and purity. The appearance may vary slightly based on synthesis and handling conditions, but it is generally characterized by its crystalline nature.

Comment on solubility

Solubility of 3-(2-amino-1-hydroxy-ethyl)phenol (C9H13NO3)

The solubility of 3-(2-amino-1-hydroxy-ethyl)phenol is an interesting characteristic that can influence its applications in various chemical processes. This compound, given its functional groups, exhibits a unique solubility profile:

  • Water Solubility: 3-(2-amino-1-hydroxy-ethyl)phenol is generally considered to be soluble in water due to the presence of hydroxyl (-OH) and amino (-NH2) groups. These polar functional groups enhance its ability to interact with water molecules.
  • Solvent Compatibility: In addition to water, this compound can be soluble in various organic solvents such as ethanol and methanol, depending on the specific conditions and concentrations.
  • Temperature Influence: As with many organic compounds, the solubility may increase with temperature, which is vital for processes that involve heating or varying solubility conditions.

It is essential to note that solubility can be influenced by several factors, including:

  1. pH of the solution - the amino group may ionize, affecting solubility.
  2. Presence of other solutes - interactions with other compounds in solution can either increase or decrease solubility.
  3. Concentration of the compound - higher concentrations can lead to saturation.

In conclusion, while 3-(2-amino-1-hydroxy-ethyl)phenol possesses good solubility characteristics, understanding these nuances is crucial for effectively utilizing its chemical properties in practical applications.

Interesting facts

Interesting Facts about 3-(2-amino-1-hydroxy-ethyl)phenol

3-(2-amino-1-hydroxy-ethyl)phenol, often referred to in the scientific community by its abbreviated name, plays a crucial role in various chemical and biological applications. Here are some intriguing aspects about this compound:

  • Biological Significance: This compound is structurally related to important biological molecules, making it a valuable target for medicinal chemistry.
  • Antioxidant Properties: The phenolic structure offers potential antioxidant capabilities. This can be significant for protecting cells from oxidative stress.
  • Building Block: It serves as an essential precursor in the synthesis of pharmacologically active compounds. Its unique functional groups allow for various chemical modifications.
  • Research Applications: Scientists often explore this compound in studies related to drug delivery and formulation, emphasizing its versatility in pharmaceutical sciences.

As with many organic compounds, its functionalization can lead to derivatives with enhanced properties or new activities. For students and chemists alike, understanding the characteristics of 3-(2-amino-1-hydroxy-ethyl)phenol provides insights into the broader realm of aromatic compounds and their reactivity.

In the words of a noted chemist, "Every compound tells a story of its formation and potential applications; it’s up to us to read and translate that story into innovations."

Synonyms
Norfenefrine
Norphenylephrine
536-21-0
3-(2-Amino-1-hydroxyethyl)phenol
Norphenephrine
Metacardiol
m-Octopamine
15308-34-6
Normetol
Norenol
Norfenefrine [INN]
DL-Norphenylephrine
m-Hydroxyphenylethanolamine
Norfenefrina
Norfenefrinum
R,S-Norphenylephrine
1-(m-Hydroxyphenyl)-2-aminoethanol
3-(2-Amino-1-hydroxy-ethyl)-phenol
alpha-(Aminomethyl)-m-hydroxybenzyl alcohol
D2P3M6SRN5
1-(3'-Hydroxyphenyl)-2-aminoethanol
WV 569 [as hydrochloride]
Norfenefrine (INN)
1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane
NORFENEFRINE [MI]
Normezaton; Norphenephrine
WV569 FREE BASE
WV-569 FREE BASE
NORFENEFRINE [WHO-DD]
DTXSID3048314
Normetasympathol
BENZYL ALCOHOL, alpha-(AMINOMETHYL)-m-HYDROXY-
3-octopamine
DL-m-Octopamine
Benzenemethanol, .alpha.-(aminomethyl)-3-hydroxy-
.ALPHA.-(AMINOETHYL)-M-HYDROXYBENZYL ALCOHOL
.ALPHA.-(AMINOMETHYL)-M-HYDROXYBENZYL ALCOHOL.
.ALPHA.-(AMINOMETHYL)-3-HYDROXYBENZENE METHANOL
(+-)-Norphenylephrine
WV 569 (AS HYDROCHLORIDE)
Norfenefrinum [INN-Latin]
Norfenefrina [INN-Spanish]
benzene, 1-(2-amino-1-hydroxy)ethyl-3-hydroxy-
NCGC00167553-01
EINECS 208-626-8
UNII-D2P3M6SRN5
BRN 1211018
Norfenefrin
norfenefrine, (+,-)-isomer
(+-)-alpha-(Aminomethyl)-m-hydroxybenzyl alcohol
Zondel (Salt/Mix)
Novadral (Salt/Mix)
Benzenemethanol, alpha-(aminomethyl)-3-hydroxy-, (+-)-
2-amino-1-(3-hydroxyphenyl)ethan-1-ol
BENZYL ALCOHOL, alpha-(AMINOMETHYL)-m-HYDROXY-, (+-)-
alpha-(aminomethyl)-3-hydroxybenzyl alcohol
(.+/-.)-Norfenefrine
alpha-(Aminomethyl)-3-hydroxybenzene methanol
DL-[2-hydroxy-2-(3-hydroxyphenyl)ethyl]amine
Oprea1_016194
3-13-00-02235 (Beilstein Handbook Reference)
SCHEMBL153494
CHEMBL358040
DTXCID1028289
C01CA05
CHEBI:134779
ALBB-006272
HY-B1711
BBL028398
STK503797
3-(2-Amino-1-hydroxyethyl)phenol #
AKOS005171592
DB13378
FS-4505
(r)-3-(2-Amino-1-hydroxyethyl)phenol
NCGC00167553-02
13026-50-1
DA-56255
3-[(1rs)-2-amino-1-hydroxyethyl]phenol
DB-043177
(1RS)-2-amino-1-(3-hydroxyphenyl)ethanol
CS-0013711
NS00004553
.alpha.-(Aminomethyl)-m-hydroxybenzyl alcohol
EN300-96556
D08286
G15814
SBI-0653927.0001
ALPHA-(AMINOETHYL)-M-HYDROXYBENZYL ALCOHOL
Benzyl alcohol, .alpha.-(aminomethyl)-m-hydroxy-
SR-01000944512
ALPHA-(AMINOMETHYL)-M-HYDROXYBENZYL ALCOHOL.
SR-01000944512-1
Q12746348
ETILEFRINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride, (+/-)-
Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride, (A+/-)-
208-626-8
Norphenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material