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Folinic acid

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Identification
Molecular formula
C20H23N7O7
CAS number
58-05-9
IUPAC name
[[3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propoxy]-hydroxy-phosphoryl] phosphono hydrogen phosphate
State
State

At room temperature, folinic acid is generally found in a solid state.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
474.44g/mol
Molar mass
474.4410g/mol
Density
2.3400g/cm3
Appearence

Folinic acid appears as a white to slightly yellow crystalline powder. It is typically odorless and is noted for its stability under normal conditions.

Comment on solubility

Solubility of [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propoxy]-hydroxy-phosphoryl phosphono hydrogen phosphate

The solubility of this complex compound, C20H23N7O7, can be understood through several factors:

  1. Polarity: Due to the presence of multiple functional groups such as amines, hydroxyls, and phosphate groups, the compound exhibits a high degree of polarity. This suggests that it may be soluble in polar solvents, particularly water.
  2. Hydrogen Bonding: The hydroxyl (-OH) and amine (-NH2) groups can form hydrogen bonds with water molecules, enhancing solubility. As the number of hydrogen bonds increases, so does the potential for the compound to dissolve.
  3. Ionization: Being a phosphonic acid derivative, this compound can ionize in solution, which generally increases solubility in water. The presence of charged species often facilitates interactions with polar solvent molecules.

In terms of practical observations:

  • The compound's solubility in water is highly favorable compared to many organic compounds.
  • It may show limited solubility in non-polar solvents due to its structural characteristics.
  • Temperature can also affect the solubility; higher temperatures typically increase solubility for many compounds.

In summary, considering its structural attributes and the nature of interactions within a solvent, [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propoxy]-hydroxy-phosphoryl phosphono hydrogen phosphate likely exhibits good solubility in polar solvents, particularly water.

Interesting facts

Interesting Facts about [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propoxy]-hydroxy-phosphoryl phosphono hydrogen phosphate

This complex compound is a fascinating example of chemical architecture that intersects biology and chemistry. Below are some intriguing aspects that highlight its significance:

  • Biochemical Relevance: Compounds like this one are often studied for their roles as nucleotides or nucleotide analogs, which are crucial in metabolic pathways and the synthesis of nucleic acids.
  • Phosphorylation: The presence of phosphate groups suggests that this compound may participate in phosphorylation reactions, modifying proteins and enzymes, which can be pivotal in regulating biological functions.
  • Structural Complexity: With multiple functional groups, including amine and hydroxy features, this compound exemplifies the diversity of interactions that can occur, leading to unique biochemical properties.
  • Potential Drug Development: Compounds with similar structures are often researched for their potential as pharmaceuticals, particularly in targeting specific biological pathways, leading to therapeutic advancements.

"Chemistry is the science of matter, but I prefer to see it as the science of change." - Walter White

In summary, while the detailed structure of [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propoxy]-hydroxy-phosphoryl phosphono hydrogen phosphate may seem daunting, its implications in biological systems and potential therapeutic applications make it a compelling subject for ongoing research and study.