Folic Acid | Solubility of Things

Identification

Molecular formula

C₁₉H₁₉N₇O₆

CAS number

59-30-3

IUPAC name

[3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propyl] dihydrogen phosphate

State

At room temperature, folic acid is a stable solid. It is commonly supplied as a dry powder and is used in formulations requiring careful weight measurement due to its critical nutritional significance.

Melting point (Celsius)

250.00

Melting point (Kelvin)

523.00

Boiling point (Celsius)

314.00

Boiling point (Kelvin)

587.00

General information

Molecular weight

441.40g/mol

Molar mass

441.4040g/mol

Density

1.8000g/cm³

Appearence

Folic acid appears as a yellow or orange crystalline powder. It is sensitive to light and degrades upon exposure to ultraviolet (UV) radiation. Its chemical stability is preserved best when stored in the dark and at low temperatures.

Comment on solubility

Solubility of [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propyl] dihydrogen phosphate

The solubility of the compound [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propyl] dihydrogen phosphate, with the chemical formula C₁₉H₁₉N₇O₆, is influenced by several key factors:

Polarity: Compounds containing polar functional groups, like the phosphate group here, tend to exhibit greater solubility in polar solvents such as water.
Hydrogen Bonding: The presence of hydroxyl (-OH) groups allows for significant hydrogen bonding interactions with solvent molecules, enhancing solubility.
Molecular Size: With a sizable molecular weight, the solubility may be somewhat limited compared to smaller compounds, although the flexible structure may still facilitate solvation.

In summary, while predicting the exact solubility without empirical data can be challenging, it is likely that this compound exhibits notable solubility in aqueous solutions due to its polar nature and ability to engage in hydrogen bonding. As the saying goes, "Like dissolves like," and the combination of polar groups in this structure suggests it will readily interact with water.

Interesting facts

Interesting Facts about [3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propyl] dihydrogen phosphate

[3-(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)-2,3-dihydroxy-propyl] dihydrogen phosphate is an intriguing compound that showcases the blend of biochemistry and medicinal chemistry. This compound features a complex structure that is primarily linked to the biology of nucleic acids and enzymes.

Key Highlights:

Biological Role: This compound is a derivative of pteridine, which plays a significant role in the biochemical pathways of folate metabolism. Pteridines are vital for cellular function, affecting DNA synthesis and repair.
Phosphate Group Importance: The dihydrogen phosphate moiety is crucial in biochemistry; it is involved in energy transfer through ATP (adenosine triphosphate) and activates several enzymes in metabolic pathways.
Potential Therapeutics: Due to its structural complexity, it holds promise for research into new therapeutic agents that target specific pathways in diseases such as cancer and neurodegenerative disorders.
Research Applications: Its role in cellular processes makes it an interesting subject for studies in drug development, particularly regarding anti-cancer therapies and the influence of nucleotides on gene expression.

This compound exemplifies the critical interplay between structure and function in biochemistry. As researchers delve deeper into its properties, there is potential for significant advancements in both treatment strategies and our understanding of complex biological systems. In the words of a renowned biochemist, "Every molecule tells a story; it's our job to decipher it."