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Lorediplon

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Identification
Molecular formula
C20H24N2O
CAS number
1431973-00-0
IUPAC name
3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one
State
State

At room temperature, Lorediplon is typically a solid. This indolinone derivative tends to maintain a crystalline solid state under typical laboratory conditions, making it manageable for handling and formulation purposes.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
322.42g/mol
Molar mass
322.4230g/mol
Density
1.2000g/cm3
Appearence

Lorediplon typically appears as a crystalline powder. Its specific color and texture may vary depending on the degree of purity and the method of preparation, but it often has a white to off-white coloration in its pure form.

Comment on solubility

Solubility of 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one

The compound 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one is of particular interest when it comes to its solubility characteristics. Understanding its solubility is crucial for various applications, especially in pharmaceutical formulations. Here are some key points regarding its solubility:

  • Solvent Dependence: This compound tends to exhibit variable solubility based on the choice of solvent. It is often more soluble in polar solvents due to the presence of amino groups which can engage in hydrogen bonding.
  • Temperature Influence: As with many organic compounds, increasing the temperature can enhance its solubility. Careful consideration should be given to the melting point of the compound to avoid degradation.
  • pH Sensitivity: The solubility can also be pH-dependent, particularly due to the amino groups which may lead to protonation under acidic conditions, increasing solubility.
  • Practical Applications: In the context of drug formulation, assessing solubility is vital for the bioavailability of the compound in the human body.

In summary, the solubility of 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one is influenced by several factors including solvent choice, temperature, and pH levels. Understanding these parameters is essential for effectively utilizing the compound in various chemical applications.

Interesting facts

Interesting Facts about 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one

The compound 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one is a fascinating member of the indole family, known for its unique structural features and potential applications in medicinal chemistry. Here are some captivating insights about this compound:

  • Bioactivity: This compound has garnered attention for its potential pharmacological properties, particularly in the realm of antidepressants and neuroprotective agents. Its unique structure may contribute to its ability to interact with biological systems.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step organic reactions, showcasing the intricate techniques employed in modern synthetic organic chemistry. The presence of the dimethylamino group plays a critical role in enhancing the compound’s biological efficacy.
  • Structure-Activity Relationship: Scientists are keenly interested in exploring the structure-activity relationship (SAR) of this compound. Modifications to its indolin core can significantly impact its biological activity, providing a rich avenue for research and development.
  • Potential in Cancer Research: Some derivatives of this compound have shown promise in preliminary studies targeting various cancer types. The indole moiety is often associated with anticancer activities, making this compound a candidate for further exploration in oncology.
  • Research Applications: As researchers dive deeper into the realm of drug discovery, compounds like 3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-indolin-2-one serve as crucial intermediates in the development of more potent therapeutic agents. Its properties may offer valuable insights into designing new medications.

As we continue to unravel the complexities of this compound, its potential applications in various fields underline the importance of interdisciplinary collaboration in advancing chemical research. With each study, we inch closer to unlocking new therapeutic avenues that could improve human health.

Synonyms
18176-31-3
BRN 0491434
3-(2-Aminoethyl)-1-(dimethylamino)-3-phenyl-2-indolinone
2-INDOLINONE, 3-(2-AMINOETHYL)-1-(DIMETHYLAMINO)-3-PHENYL-
DTXSID60939468
3-(2-aminoethyl)-1-(dimethylamino)-3-phenyl-1,3-dihydro-2H-indol-2-one