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Serotonin

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Identification
Molecular formula
C10H12N2O
CAS number
50-67-9
IUPAC name
3-(2-aminoethyl)-1H-indol-4-ol
State
State

At room temperature, serotonin is typically found as a solid.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.00
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.00
General information
Molecular weight
176.22g/mol
Molar mass
176.2150g/mol
Density
1.4000g/cm3
Appearence

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a white to slightly beige crystalline powder. It may appear pale yellow when exposed to air and light.

Comment on solubility

Solubility of 3-(2-aminoethyl)-1H-indol-4-ol

The solubility of the compound 3-(2-aminoethyl)-1H-indol-4-ol can be examined from several angles, mainly based on its molecular structure and functional groups present. Here are some key points to consider:

  • Hydrophilicity vs Hydrophobicity: The presence of the amino group in the structure typically enhances the compound's ability to interact with water, suggesting a degree of hydrophilicity.
  • Polarity: The indole ring contributes to the overall polarity of the molecule, affecting solubility in polar solvents like water.
  • Solvent Types: This compound is expected to be more soluble in polar solvents compared to non-polar solvents, owing to the interactions of the amino group.
  • Effect of pH: The solubility may also vary with pH due to protonation and deprotonation processes associated with the amino group.

In summary, while predicting the exact solubility of 3-(2-aminoethyl)-1H-indol-4-ol may require empirical testing, the presence of multiple functional groups suggests that it exhibits notable solubility in polar solvents. As a rule of thumb, compounds with amino groups tend to be more soluble in water. However, actual solubility values may vary significantly based on the specific conditions and solvent used.

Interesting facts

Interesting Facts about 3-(2-aminoethyl)-1H-indol-4-ol

3-(2-aminoethyl)-1H-indol-4-ol, often referred to as a derivative of indole, highlights the fascinating intersection between organic chemistry and biological systems. This compound is part of a larger group of molecules known for their roles in various biological processes.

Key Characteristics

  • Indole Backbone: The indole structure is notable in many natural products and pharmaceuticals.
  • Biological Activity: Compounds like this one are often studied for their potential therapeutic effects, making them important in drug development.
  • Amine Functionality: The aminoethyl side chain can enhance its reactivity and interaction with biological targets.

Researchers focus on this compound due to its intriguing properties, which may contribute to:

  1. Neurotransmitter Activity: Compounds similar in structure have been linked to the modulation of neurotransmitters, influencing mood and cognition.
  2. Antioxidant Properties: The indole derivative may exhibit protective effects against oxidative stress.
  3. Potential as a Biomarker: Its presence or levels in biological systems could serve as indicators of certain diseases.

As quoted by many in the field, "Understanding complex compounds like 3-(2-aminoethyl)-1H-indol-4-ol is crucial for unraveling the intricacies of life itself." The exploration of such compounds opens doors to new therapeutic avenues and deepens our comprehension of biological chemistry.

Synonyms
4-HYDROXYTRYPTAMINE
3-(2-aminoethyl)-1H-indol-4-ol
UNII-DP0D1701D1
DP0D1701D1
3-(2-aminoethyl)-indol-4-ol
CHEBI:139217
DTXSID30205607
DTXCID20128098
836-014-6
570-14-9
CHEMBL18855
SCHEMBL1459770
BDBM50024203
PDSP1_000531
PDSP2_000529
3-(2-Amino-ethyl)-1H-indol-4-ol
AKOS005208092
PD094269
3-(2-Amino-ethyl)-1H-indol-4-ol(4-HT)
C21762
EN300-372905
Q27276515