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Serotonin p-aminobenzoate

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Identification
Molecular formula
C17H17N3O2
CAS number
13496-56-3
IUPAC name
[3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate
State
State

The compound is typically a solid at room temperature. It is stable and maintains its structural integrity under normal conditions.

Melting point (Celsius)
221.00
Melting point (Kelvin)
494.00
Boiling point (Celsius)
436.60
Boiling point (Kelvin)
709.80
General information
Molecular weight
337.37g/mol
Molar mass
337.3670g/mol
Density
1.2300g/cm3
Appearence

The compound appears as a white to off-white crystalline powder. It is visually characterized by its crystal structure, which may vary in size but typically presents as fine crystalline granules.

Comment on solubility

Solubility of [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate

The solubility of the compound [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate can be influenced by various factors, leading to interesting outcomes in different solvents. Here are some key points regarding its solubility:

  • Polar Solvents: Compounds that contain amino groups often demonstrate increased solubility in polar solvents such as water and alcohols. This is attributed to hydrogen bonding and ionic interactions.
  • Non-polar Solvents: On the contrary, solubility in non-polar solvents is typically low. This is due to the hydrophobic nature of the indole ring, which doesn't interact favorably with non-polar environments.
  • pH Influence: The solubility can also vary with pH; for instance, the ionization state of the amino groups can promote or hinder solubility, making it more soluble in acidic or basic conditions.
  • Temperature Effects: Increasing the temperature generally enhances solubility for many compounds; thus, warming the solvent might be beneficial for dissolution.

As a rule of thumb, compounds similar to [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate are better soluble in aqueous solutions compared to organic solvents, emphasizing the importance of functional groups in determining solubility characteristics. Understanding these aspects can significantly impact their applications in pharmaceutical formulations and other chemical processes.

Interesting facts

Intriguing Insights into [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate

[3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate is a fascinating compound that merges the worlds of indole and amino benzoic acid derivatives, showcasing a blend of biological significance and potential medicinal applications.

Biological Relevance

This compound is noteworthy for its role in various biological processes; here are a few key points:

  • Drug Discovery: Compounds with indole derivatives are frequently studied for their pharmacological properties, including anti-cancer, anti-inflammatory, and anti-microbial activities.
  • Neurotransmitter Modulation: The presence of the aminoethyl group suggests that it may interact with neurotransmitter pathways, lending potential as a neuroactive agent.
  • Targeting Specific Enzymes: Research indicates that such compounds can be developed to target specific enzymes involved in metabolic pathways, paving the way for targeted therapies.

Applications in Research

Investigating [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate can reveal much about compound design and synthesis:

  • Chemical Synthesis: The synthesis of this compound serves as an excellent example of multi-step reactions, emphasizing the importance of functional group manipulation.
  • Analytical Techniques: The compound can be analyzed using techniques such as NMR spectroscopy and mass spectrometry to determine its structural properties and purity.

Quote from the Literature

As noted in recent studies, "the structural complexity of indole-based compounds continues to inspire innovative approaches in drug design and synthesis."

In summary, [3-(2-aminoethyl)-1H-indol-5-yl] 4-aminobenzoate not only represents an intriguing intersection of chemical architecture but also holds promise for future research in medicinal chemistry and biochemistry, making it a valuable topic of study for both experienced chemists and emerging scientists alike.

Synonyms
O-(p-aminobenzoyl)-serotonin