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5-HTP benzyl ester

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Identification
Molecular formula
C19H18N2O2
CAS number
962-58-3
IUPAC name
[3-(2-aminoethyl)-1H-indol-5-yl] benzoate
State
State

At room temperature, the compound is typically a solid. It is stable under standard conditions.

Melting point (Celsius)
142.50
Melting point (Kelvin)
415.65
Boiling point (Celsius)
368.10
Boiling point (Kelvin)
641.25
General information
Molecular weight
294.34g/mol
Molar mass
294.3370g/mol
Density
1.2610g/cm3
Appearence

This compound typically appears as a white to off-white powder. The exact shade and texture may vary slightly based on purity and specific conditions during crystallization.

Comment on solubility

Solubility of [3-(2-aminoethyl)-1H-indol-5-yl] benzoate

The solubility profile of [3-(2-aminoethyl)-1H-indol-5-yl] benzoate is an intriguing subject that combines both polar and nonpolar characteristics due to the presence of its complex molecular structure.

Here are some key considerations regarding its solubility:

  • Polarity: The amino group (-NH2) present in the compound enhances its polarity, which may contribute to its solubility in polar solvents such as water.
  • Hydrophobic regions: The indole and benzoate moieties contain hydrophobic regions, which can lead to decreased solubility in highly polar solvents.
  • pH Influence: The solubility may also be affected by the pH of the solution; at certain pH levels, the amino group can become protonated, enhancing solubility in aqueous environments.
  • Solvent Compatibility: This compound may exhibit better solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO), due to the balance between hydrophilic and hydrophobic characteristics.

In summary, the solubility of [3-(2-aminoethyl)-1H-indol-5-yl] benzoate is governed by a combination of its structural features and the nature of the solvent. Understanding these parameters is crucial for applications in fields such as pharmaceuticals, where solubility can significantly impact bioavailability.

Interesting facts

Interesting Facts about [3-(2-aminoethyl)-1H-indol-5-yl] benzoate

[3-(2-aminoethyl)-1H-indol-5-yl] benzoate is a fascinating compound that garners attention due to its unique structural features and potential applications in various fields. This compound is derived from the indole group, which is a significant structural motif in many biologically active molecules.

Key Highlights:

  • Indole Backbone: The indole ring is known for its prominence in pharmaceuticals, serving as the foundation for various medications, including antidepressants and anti-cancer drugs.
  • Aminoethyl Derivative: The presence of the aminoethyl group suggests potential interactions with biological systems, making it valuable for drug design and development.
  • Potential Biological Activity: Compounds containing indole derivatives, such as this one, have been studied for their antitumor, analgesic, and antimicrobial activities, which are of high interest in medicinal chemistry.

This compound can serve as a building block for synthesizing more complex molecules, allowing researchers to explore new avenues in pharmacology. The versatility of the indole structure combined with the aminoethyl functionality enhances the potential for complex biological interactions. As noted by one researcher, "The beauty of indole chemistry lies in its ability to bridge various therapeutic areas."

Furthermore, the benzoate group in the compound can influence its pharmacokinetic properties, such as absorption and distribution in biological systems, making it an intriguing subject for further studies.

In summary, [3-(2-aminoethyl)-1H-indol-5-yl] benzoate exemplifies how modifying a well-known scaffold can yield new compounds with promising biological properties. Researchers continue to delve deeper into the implications of such compounds, aiming to unveil their potential in treating various diseases.

Synonyms
SCHEMBL27195479
SCHEMBL30888861