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Serotonin

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Identification
Molecular formula
C10H12N2O2
CAS number
50-67-9
IUPAC name
3-(2-aminoethyl)-1H-indole-5,6-diol
State
State

Serotonin is typically a solid at room temperature. As a neurotransmitter in biological systems, it appears as part of biochemical pathways in solution.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.15
Boiling point (Celsius)
509.40
Boiling point (Kelvin)
782.55
General information
Molecular weight
176.22g/mol
Molar mass
176.2150g/mol
Density
1.5453g/cm3
Appearence

Serotonin is typically a colorless to yellowish crystalline solid when isolated. In its pure form, it may appear as a powder.

Comment on solubility

Solubility of 3-(2-aminoethyl)-1H-indole-5,6-diol

The solubility of 3-(2-aminoethyl)-1H-indole-5,6-diol is an intriguing aspect of its chemical behavior, influenced by both its structure and functional groups. This compound contains a hydroxyl group, which typically enhances its solubility in polar solvents. Below are some key points regarding its solubility:

  • Polar Solvents: Due to the presence of hydroxyl (-OH) groups, 3-(2-aminoethyl)-1H-indole-5,6-diol is likely to be soluble in water and other polar solvents.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents is expected to be low, as the hydrophobic regions of the indole structure may resist solvation.
  • Temperature Effects: Generally, increasing the temperature can enhance solubility, so it may dissolve better in heated water or polar organic solvents.
  • pH Influence: The presence of amino groups may allow for ionization at different pH levels, potentially affecting solubility. For example, at higher pH, the amino group can become deprotonated, enhancing solubility in alkaline solutions.

In summary, 3-(2-aminoethyl)-1H-indole-5,6-diol is likely to be soluble in polar solvents, and its solubility may vary with temperature and pH changes. Understanding these solubility characteristics is crucial for its application in various chemical processes.

Interesting facts

Interesting Facts about 3-(2-aminoethyl)-1H-indole-5,6-diol

3-(2-aminoethyl)-1H-indole-5,6-diol is a fascinating compound that belongs to the indole class of organic compounds, which are notable for their rich chemistry and diverse biological activities. Here are some intriguing insights into this compound:

  • Biological significance: Compounds of the indole family, including 3-(2-aminoethyl)-1H-indole-5,6-diol, often exhibit various biological activities. They can play crucial roles in the pharmaceutical industry, serving as precursors for the synthesis of important medications.
  • Potential therapeutic applications: Research indicates that this compound, with its aminoethyl side chain, may have neuroprotective properties and could be explored for potential use in treating neurodegenerative diseases.
  • Natural occurrence: Indole derivatives are commonly found in nature, particularly in plants and animal tissues, where they often serve as signaling molecules or contribute to metabolic processes.
  • Structural uniqueness: The presence of the diol functional group adds to the chemical versatility of this compound, potentially affecting its reactivity and interaction with other biological molecules.
  • Research interest: As scientists continue to probe the functionalities of indole derivatives, 3-(2-aminoethyl)-1H-indole-5,6-diol stands out as a compound of interest, highlighting the relationship between structure and biological activity.

In summary, 3-(2-aminoethyl)-1H-indole-5,6-diol represents a unique intersection of chemistry and biology, making it an exciting area of study for chemists and pharmacologists alike. It embodies the beauty and complexity of organic molecules that play vital roles in life sciences.

Synonyms
5,6-Dihydroxytryptamine
3-(2-Aminoethyl)-1H-indole-5,6-diol
1H-Indole-5,6-diol, 3-(2-aminoethyl)-
3-(2-Aminoethyl)indole-5,6-diol
BRN 0475698
EINECS 225-810-3
UNII-W2QY253O8S
INDOLE-5,6-DIOL, 3-(2-AMINOETHYL)-
W2QY253O8S
DTXSID40198930
5-22-12-00350 (Beilstein Handbook Reference)
5,6 Dihydroxytryptamine
DTXCID00121421
5090-36-8
CHEMBL303916
SCHEMBL3807782
SKOKLDQYOKPCPU-UHFFFAOYSA-N
FAA09036
BDBM50012672
PDSP1_000539
PDSP2_000537
AKOS006279613
PD094267
3-(2-Amino-ethyl)-1H-indole-5,6-diol
NS00032168
2-(5,6-Dihydroxy-1H-indol-3-yl)-ethyl-ammonium
L000696
Q27292226
2-(5,6-Dihydroxy-1H-indol-3-yl)-ethyl-ammonium(5,6-DHT)