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Bicifadine

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Identification
Molecular formula
C24H31NO
CAS number
82692-94-4
IUPAC name
3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol
State
State

At room temperature, it is a solid with a crystalline form.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
382.52g/mol
Molar mass
382.5170g/mol
Density
1.1300g/cm3
Appearence

The compound Bicifadine typically appears as a white to off-white crystalline powder. The precise texture may vary, but it usually maintains a consistent granular form.

Comment on solubility

Solubility of 3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol

The solubility of 3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol in various solvents is influenced by its complex molecular structure. This compound features both hydrophobic and hydrophilic elements, making its solubility characteristics quite fascinating. Key factors that govern its solubility include:

  • Polarity: The presence of polar hydroxyl groups contributes to increased solubility in polar solvents like water.
  • Hydrophobic Interactions: The bulky diphenyl group may lead to decreased solubility in water due to its hydrophobic nature.
  • Solvent Type: This compound is likely to dissolve well in organic solvents such as ethanol and methanol, which can accommodate both its hydrophilic and hydrophobic portions.
  • Temperature: Increasing the temperature often enhances solubility, particularly for organic compounds in organic solvents.

As a result, one might find that 3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol is more soluble in organic solvents and exhibits limited solubility in water. Such a profile is typical for complex organic molecules with significant hydrophobic character.

Interesting facts

Interesting Facts about 3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol

This fascinating compound, known for its complexity and unique structural features, is a member of the family of bicyclic amines. Here are some engaging aspects about this compound:

  • Bicyclic Architecture: The incorporation of a 2-azabicyclo[2.2.2]octane structure contributes to its interesting three-dimensional conformation. This feature is often associated with enhanced biological activity and interaction with various receptors.
  • Pharmaceutical Relevance: Compounds with a similar structure have been explored in medicinal chemistry for their potential roles as antidepressants, analgesics, and for neuroprotective effects. This makes it a compound of interest in drug discovery research.
  • Synthetic Routes: The synthesis of this compound often involves innovative strategies in organic chemistry, especially utilizing stereoselective synthesis to ensure the correct orientation of atoms, significantly impacting the compound's biological properties.
  • Binding Affinity: The unique substituents, like the 1,1-diphenyl group, may enhance the compound's binding affinity to selective receptors in the human body, which can lead to a better understanding of its pharmacodynamics.
  • Research Opportunities: The structure of this compound opens doors to extensive research opportunities in the fields of neuropharmacology and medicinal chemistry, where the interaction with neurological pathways could yield promising results.

Understanding compounds like 3-(2-azabicyclo[2.2.2]octan-2-yl)-1,1-diphenyl-butan-1-ol is crucial as they may serve as core structures for developing a new generation of therapeutic agents. Their rich chemistry and biological activity continue to captivate scientists and spark new ideas in drug design.